ID A0A1G8YEG8_9ACTN Unreviewed; 742 AA.
AC A0A1G8YEG8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
DE Flags: Fragment;
GN ORFNames=SAMN05421874_104381 {ECO:0000313|EMBL:SDK01319.1};
OS Nonomuraea maritima.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=683260 {ECO:0000313|EMBL:SDK01319.1, ECO:0000313|Proteomes:UP000198683};
RN [1] {ECO:0000313|EMBL:SDK01319.1, ECO:0000313|Proteomes:UP000198683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5681 {ECO:0000313|EMBL:SDK01319.1,
RC ECO:0000313|Proteomes:UP000198683};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FNFB01000004; SDK01319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G8YEG8; -.
DR STRING; 683260.SAMN05421874_104381; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000198683; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SDK01319.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000198683};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 524..737
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:SDK01319.1"
SQ SEQUENCE 742 AA; 79399 MW; FE50A53566AFD68A CRC64;
RWQDVDDILA AGIDVVSTVN IQHLESVNDV VREITGVVQR ETVPDEVVRR ADQIELVDMS
AEALRRRLAH GNVYPPEKVD AALANYFRAG NLIALRELAL LWVAGKVDDQ LDRYRAEHGI
ARTWETRERV VVALTGGPEG ETLVRRAARI AARTKGADLL AVHVTSADGP AGGDPAGLSR
QRLLVESLGG TYHQVVGEDI PRALLDFARG VNATQLVLGA SRRRRFAQVL SRGVGVETIA
RSGSIDVHMV THDEARAGRR PRSRAALTRK RRITGWVLAV AGMPLLTATL APFREVLSLP
SEILLFLCLT VGVALIGGTW PAITTAVGGS LMLNWFFTRP IGRFTINDPE NLFALVVFVL
VAAAVSAIVD LAARRTREAA RASADAALLS TLAGHVLRGE AAVPSLLERT RVTFGLTSVT
LLERRPEAAR TPDHQSDPDA WRIVATCGGA PSTCPGLSDT DVRIDDTLVL AATGRLLDAA
DRTVLEAFAA ETAVALRQER LQQEAARAEP LAEADKMRTA LLAAVSHDLR SPLASAKAAI
ESLANTGVAW SDHDRAELLD TAAESLAKLD RLVANLLDMS RLQAGVLGVT TQPIALEEIV
PRAVDDLGPL RDQIEGDISV ELPEIAADPA LLERVLVNLM SNAVRYSPPG RNVLVSASRH
GEQVEIRVMD RGPGIPPGAH DRVFQPFQRL GDRDNHSGVG LGLALSRGLT EAMGGTLVPD
ETPGGGLTMI LTMPIAVRGV PA
//
