ID A0A1G9A4R4_9GAMM Unreviewed; 493 AA.
AC A0A1G9A4R4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Sodium/proton antiporter, NhaD family (TC 2.A.62) {ECO:0000313|EMBL:SDK21440.1};
GN ORFNames=SAMN04487954_11327 {ECO:0000313|EMBL:SDK21440.1};
OS Halomonas gudaonensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=376427 {ECO:0000313|EMBL:SDK21440.1, ECO:0000313|Proteomes:UP000198525};
RN [1] {ECO:0000313|EMBL:SDK21440.1, ECO:0000313|Proteomes:UP000198525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.6133 {ECO:0000313|EMBL:SDK21440.1,
RC ECO:0000313|Proteomes:UP000198525};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter
CC family. {ECO:0000256|ARBA:ARBA00025753}.
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DR EMBL; FNES01000013; SDK21440.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9A4R4; -.
DR STRING; 376427.SAMN04487954_11327; -.
DR OrthoDB; 9772058at2; -.
DR Proteomes; UP000198525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR045016; NhaD-like.
DR NCBIfam; NF038006; NhaD_1; 1.
DR PANTHER; PTHR43269; SODIUM/PROTON ANTIPORTER 1-RELATED; 1.
DR PANTHER; PTHR43269:SF2; SODIUM_PROTON ANTIPORTER 1-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198525};
KW Signal {ECO:0000256|SAM:SignalP}; Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..493
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011753122"
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..434
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 493 AA; 54774 MW; 99323909AFFFDDEA CRC64;
MVTCPRSSDH RHPTRWSFWF CAPLLFLGLS TPLHAAAGPL DLTPSAVGMA ALALFVLAYA
LVMAEEKIHM RKSKPVLVAA GIIWAMIGWV YVNAGLSTES EHAFRETLLE FSELMLFLLV
AMTYINAMEE RRVFDALRSW MIRKGFSYKQ LFWLTGGLAF VISPVADNLT TALLMCAVVT
KVAEGDKRFI NLCCINIVVA ANAGGAFSPF GDITTLMVWQ AGMVEFYEFL SLFIPSLVNF
LIPAVVMSLF INNRKPEGVY EDVWLKRGAR RIIALFLLTV ATAVAGHTLL HLPPVLGMMT
GLGYLQFFGY YLRRTLPRSL ERKRKRYTRR GDYRKLEQLG SVVPFDVFNR VARAEWDTLL
FFYGVVMCVG GLGFMGYLAT MSELLYTQWD ATWANVVLGL ISAVIDNIPV MFAVLTMEPE
MSHGHWLLVT LTAGVGGSLL SVGSAAGVAV MGQSRGAYTF MGHLRWAPVI MLGYIASIAV
HLWLNAESFA IMH
//
