ID   A0A1G9D2C5_9RHOB        Unreviewed;       307 AA.
AC   A0A1G9D2C5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Isopenicillin N synthase {ECO:0000313|EMBL:SDK58080.1};
GN   ORFNames=SAMN04488026_104533 {ECO:0000313|EMBL:SDK58080.1};
OS   Aliiruegeria lutimaris.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Aliiruegeria.
OX   NCBI_TaxID=571298 {ECO:0000313|EMBL:SDK58080.1, ECO:0000313|Proteomes:UP000199382};
RN   [1] {ECO:0000313|EMBL:SDK58080.1, ECO:0000313|Proteomes:UP000199382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 25294 {ECO:0000313|EMBL:SDK58080.1,
RC   ECO:0000313|Proteomes:UP000199382};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC       family. {ECO:0000256|RuleBase:RU003682}.
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DR   EMBL; FNEK01000045; SDK58080.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G9D2C5; -.
DR   STRING; 571298.SAMN04488026_104533; -.
DR   OrthoDB; 21825at2; -.
DR   Proteomes; UP000199382; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR026992; DIOX_N.
DR   InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR   InterPro; IPR027443; IPNS-like_sf.
DR   InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR   PANTHER; PTHR47990; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR47990:SF258; FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR   Pfam; PF14226; DIOX_N; 1.
DR   PRINTS; PR00682; IPNSYNTHASE.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   PROSITE; PS51471; FE2OG_OXY; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|RuleBase:RU003682};
KW   Metal-binding {ECO:0000256|RuleBase:RU003682};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199382}.
FT   DOMAIN          169..268
FT                   /note="Fe2OG dioxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51471"
SQ   SEQUENCE   307 AA;  33849 MW;  6E764BF9F4BB0252 CRC64;
     MIPKLDWRRF SEATDREGFI SDLSAAISGP GLFRLTHHGI DPELICDAFT GSTSVFDLTE
     AEKRTLAMQA GPHNRGWARL GVERLADGSS VLERREAFNI GLELPRTDPR VATRQRFRTQ
     TPWPAIPGFR DTMLSYYDAV LELGLALHRA FAAELSLAPD CFDPLFVDPL ATLRLITYPP
     GTGSDAETGA GTHTDFGSIS LLLTDDQPGL QAKLRNGDWI DVKPDSDSFI ILLGDALECW
     TGGKYAATPH RVQSPKHRRQ AINFYLDPAP EASLSPFPGF GKAVQRPQKY VDYLAEGLSA
     AHQVMQR
//