ID A0A1G9DI68_9ACTN Unreviewed; 409 AA.
AC A0A1G9DI68;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=SAMN05421869_117149 {ECO:0000313|EMBL:SDK63558.1};
OS Nonomuraea jiangxiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=633440 {ECO:0000313|EMBL:SDK63558.1, ECO:0000313|Proteomes:UP000199202};
RN [1] {ECO:0000313|EMBL:SDK63558.1, ECO:0000313|Proteomes:UP000199202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.6533 {ECO:0000313|EMBL:SDK63558.1,
RC ECO:0000313|Proteomes:UP000199202};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; FNDJ01000017; SDK63558.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9DI68; -.
DR STRING; 633440.SAMN05421869_117149; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000199202; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000199202}.
FT DOMAIN 151..399
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 409 AA; 43202 MW; DF5FDE50557D8C89 CRC64;
MSVALGTTRP LPVRTTPVGD PGDLLAALPR TAPYAWIRNG EGLVGWGEAA RVDVPPGPGR
FGWAREWLAT VFGESHVDDA VRVPGSGPVA FGSFTFDADA HGSVLVVPQA VLARRGGHAW
LTTIGDLPLE TFSPVRDPGR ISYGDGSLSA PAWEHVVARA ARRIRDGELE KVVLARDLVA
TAERPIDVRL LLTRLARRYP ECYTFSVAGL VGATPELLIR RTGQEIESLV LAGTTPRGTG
AADDLARGAA LLASPKDRYE HECAIASVRQ TLAPLCSSLE TPDEPELLML PNVQHLASHV
TGRLADGASV LDVVAAMHPT AAVGGTPTHT AIEVIRELEG MDRAGYAGPV GWIDAHGDGE
WGIALRSGLV QGRRARLFAG GGIMGDSDPA AELAEAQAKF RVMQYALEG
//
