ID A0A1G9FWY0_9ACTN Unreviewed; 454 AA.
AC A0A1G9FWY0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Arylsulfatase A {ECO:0000313|EMBL:SDK92956.1};
GN ORFNames=SAMN05421869_120105 {ECO:0000313|EMBL:SDK92956.1};
OS Nonomuraea jiangxiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=633440 {ECO:0000313|EMBL:SDK92956.1, ECO:0000313|Proteomes:UP000199202};
RN [1] {ECO:0000313|EMBL:SDK92956.1, ECO:0000313|Proteomes:UP000199202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.6533 {ECO:0000313|EMBL:SDK92956.1,
RC ECO:0000313|Proteomes:UP000199202};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PTM: The conversion to 3-oxoalanine (also known as C-formylglycine,
CC FGly), of a serine or cysteine residue in prokaryotes and of a cysteine
CC residue in eukaryotes, is critical for catalytic activity.
CC {ECO:0000256|PIRSR:PIRSR036666-50}.
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DR EMBL; FNDJ01000020; SDK92956.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9FWY0; -.
DR STRING; 633440.SAMN05421869_120105; -.
DR OrthoDB; 9777306at2; -.
DR Proteomes; UP000199202; Unassembled WGS sequence.
DR GO; GO:0008449; F:N-acetylglucosamine-6-sulfatase activity; IEA:InterPro.
DR GO; GO:0030203; P:glycosaminoglycan metabolic process; IEA:InterPro.
DR CDD; cd16147; G6S; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012251; GlcNAc_6-SO4ase.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR43108; N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43108:SF8; SD21168P; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF036666; G6S; 2.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000199202}.
FT DOMAIN 8..338
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT MOD_RES 50
FT /note="3-oxoalanine (Cys)"
FT /evidence="ECO:0000256|PIRSR:PIRSR036666-50"
SQ SEQUENCE 454 AA; 50707 MW; A032C987E0911F0C CRC64;
MAEGKSRPNI VYIVADDLET GTLGLFPNIA EELVRQGVSF ERFFVTNSWC CPSRASILRS
QYVHSHNVRT NTAPEGGFDR FHSLGLERST IGTWMQEAGY RTGLMGKYLN HYPGGTAEET
YVPPGWNEWD VPVRHLYEEY GYRLNENGRV YDYGWSEEDY LSDVLAGKAA DFITASQDPF
FLFLAPIGPH NPANPAVRHA GAFSLATAPR TPSFNQEDVS REPLWLRQRP RIQEPALDEV
DERYRTRLRS MLGVDDLVGS VVDALRESGK LNDTYIFFSS DNGFHLGTHR LKQGKTTPFE
EAIRIPLVVR GPGISPGTTN DQLAATVDLA PTFAALGGAR VPAFAEGRSL VPLLRGQPPG
EWRKNLLIEF YRPIDRSSAA QTPVPAYQAL RTRDHTYVRY ETGELQLYDL AADPYQLHNL
AQDADPGLLV GLERRLQAMM ACSGAGCREA DTRH
//
