ID   A0A1G9JAN6_9CLOT        Unreviewed;       227 AA.
AC   A0A1G9JAN6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Thymidylate kinase {ECO:0000313|EMBL:SDL34273.1};
GN   ORFNames=SAMN04487833_11734 {ECO:0000313|EMBL:SDL34273.1};
OS   Sarcina sp. DSM 11001.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Sarcina.
OX   NCBI_TaxID=1798184 {ECO:0000313|EMBL:SDL34273.1, ECO:0000313|Proteomes:UP000199127};
RN   [1] {ECO:0000313|EMBL:SDL34273.1, ECO:0000313|Proteomes:UP000199127}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11001 {ECO:0000313|EMBL:SDL34273.1,
RC   ECO:0000313|Proteomes:UP000199127};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + dTMP = ADP + dTDP; Xref=Rhea:RHEA:13517,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58369, ChEBI:CHEBI:63528,
CC         ChEBI:CHEBI:456216; EC=2.7.4.9;
CC         Evidence={ECO:0000256|ARBA:ARBA00001008};
CC   -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC       {ECO:0000256|ARBA:ARBA00009776}.
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DR   EMBL; FNFZ01000017; SDL34273.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G9JAN6; -.
DR   STRING; 1798184.SAMN04487833_11734; -.
DR   OrthoDB; 9774907at2; -.
DR   Proteomes; UP000199127; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039430; Thymidylate_kin-like_dom.
DR   PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR   PANTHER; PTHR10344:SF4; THYMIDYLATE KINASE; 1.
DR   Pfam; PF02223; Thymidylate_kin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000313|EMBL:SDL34273.1};
KW   Nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022727};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199127};
KW   Transferase {ECO:0000313|EMBL:SDL34273.1}.
FT   DOMAIN          9..179
FT                   /note="Thymidylate kinase-like"
FT                   /evidence="ECO:0000259|Pfam:PF02223"
SQ   SEQUENCE   227 AA;  25220 MW;  2A9A48907B03EB7A CRC64;
     MKKGKLYVIE GLDGSGKATQ AQALYEKLRE RGILVRKVSF PNYASDSSAP VRMYLRGDFG
     RDPSSVNAYA ASSFYAIDRF AGFKSDWGSF YENGGVIIAD RYTTSNAIHQ CAKLPRDQWD
     IFLQWLFHYE YDLLGIPAPD AVIYLLVDPE VSQKLMTGRY EGDESKKDIH EQDLEYQKKS
     AAAAAYCAGH LGWHTVRCAA GGRLRSVEEI GKEISDILAG IDPSAAD
//