ID A0A1G9KYC3_9GAMM Unreviewed; 446 AA.
AC A0A1G9KYC3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Aminopeptidase P. Metallo peptidase. MEROPS family M24B {ECO:0000313|EMBL:SDL54850.1};
GN ORFNames=SAMN05661010_01957 {ECO:0000313|EMBL:SDL54850.1};
OS Halomonas muralis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=119000 {ECO:0000313|EMBL:SDL54850.1, ECO:0000313|Proteomes:UP000198654};
RN [1] {ECO:0000313|EMBL:SDL54850.1, ECO:0000313|Proteomes:UP000198654}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14789 {ECO:0000313|EMBL:SDL54850.1,
RC ECO:0000313|Proteomes:UP000198654};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766, ECO:0000256|RuleBase:RU000590}.
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DR EMBL; FNGI01000004; SDL54850.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9KYC3; -.
DR STRING; 119000.SAMN05661010_01957; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000198654; Unassembled WGS sequence.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd01087; Prolidase; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR007865; Aminopep_P_N.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR43226:SF9; XAA-PRO AMINOPEPTIDASE; 1.
DR PANTHER; PTHR43226; XAA-PRO AMINOPEPTIDASE 3; 1.
DR Pfam; PF05195; AMP_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SMART; SM01011; AMP_N; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:SDL54850.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000198654}.
FT DOMAIN 12..147
FT /note="Aminopeptidase P N-terminal"
FT /evidence="ECO:0000259|SMART:SM01011"
SQ SEQUENCE 446 AA; 48537 MW; B80CE5F24F066E25 CRC64;
MAHDILPRPA AIGLDEYRAR REALMAALAS ADSAVLLPAG QLVTRSNDSD YDFRQNSDFH
YLSGFPEPDA LLVLLPGREA GETVLFCQDK DPAKEAWTGM RIGAAGAVEH YGIDQAFENA
ERDERLGELL DGRETLYLPL DSDAALAIAE AVRGKLGARV RQGARPPQAF ADVARLVHEQ
RLIKSDAELA LLRHAAEISA RGHVRAMRTA RPGLFEYHLQ AELEHEFLWQ GAAAPAYSTI
VGGGANACVL HYIENDSPLA AGDLVLIDAG AEFDLYAGDI TRTFPVNGHF SEAQRAVYEI
VLAAQERAVA AVAPGVTLTD IHQGVVRDLT HGLIELGLLD GELEARIEDE SYRRFYLHST
SHWLGLDVHD VGGYRHKGEP RRLLPGMVLT VEPGLYIPDA ENIPAPLRGI GIRIEDDVAV
TLDGHEVLSA AVPKRIAEIE ALMTSR
//
