ID   A0A1G9LWR3_9ACTN        Unreviewed;       424 AA.
AC   A0A1G9LWR3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE            EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE   AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN   ORFNames=SAMN05660642_00624 {ECO:0000313|EMBL:SDL66418.1};
OS   Geodermatophilus siccatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=1137991 {ECO:0000313|EMBL:SDL66418.1, ECO:0000313|Proteomes:UP000198680};
RN   [1] {ECO:0000313|EMBL:SDL66418.1, ECO:0000313|Proteomes:UP000198680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45419 {ECO:0000313|EMBL:SDL66418.1,
RC   ECO:0000313|Proteomes:UP000198680};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC         ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000799};
CC   -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC       {ECO:0000256|ARBA:ARBA00005297}.
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DR   EMBL; FNHE01000001; SDL66418.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G9LWR3; -.
DR   STRING; 1137991.SAMN05660642_00624; -.
DR   Proteomes; UP000198680; Unassembled WGS sequence.
DR   GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR015890; Chorismate_C.
DR   InterPro; IPR004561; IsoChor_synthase.
DR   NCBIfam; TIGR00543; isochor_syn; 1.
DR   PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235}.
FT   DOMAIN          159..414
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
SQ   SEQUENCE   424 AA;  43063 MW;  6B882919E0601D0F CRC64;
     MTVAAVTTPD AVTPVVTTTP LLEPPALLDL LPAAGAVSWV RRGEGLVGWG EAARLEVTGP
     RALAEAAEWW EALSAGLDVD DRAEVPGSGP VVFASIAFDP AAGTSVFVVP EVVVGRRDGA
     AWVTTTGDAD PADVLAAAPA TAPAPVGRLR YADGALDPAS WCATVAAAVA RIGAGELAKV
     VLARDLLVTA DAPLDPRALL ARLAARFPGC WTFAVDGLLG ATPELLLRRT GRELSSRVLA
     GTAPRGAGAD DQRLAAGLLA SAKDRAEHAL AVDSLVRALE PYCTTLTAPG EPQLLTLANV
     RHLATDVTGV QRRGGARGRA GLLELVGAVH PTAAVCGTPT DAAAALIGEL EGMDRGRYAG
     PVGWLDARGD GEFGLALRCA QLADDDPATA RLFAGCGIVA GSDPAAELAE TQAKFAAFQA
     ALES
//