ID A0A1G9MLW2_9ACTN Unreviewed; 608 AA.
AC A0A1G9MLW2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ABC-type multidrug transport system, ATPase and permease component {ECO:0000313|EMBL:SDL75199.1};
GN ORFNames=SAMN05216298_5055 {ECO:0000313|EMBL:SDL75199.1};
OS Glycomyces sambucus.
OC Bacteria; Actinomycetota; Actinomycetes; Glycomycetales; Glycomycetaceae;
OC Glycomyces.
OX NCBI_TaxID=380244 {ECO:0000313|EMBL:SDL75199.1, ECO:0000313|Proteomes:UP000198662};
RN [1] {ECO:0000313|EMBL:SDL75199.1, ECO:0000313|Proteomes:UP000198662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3147 {ECO:0000313|EMBL:SDL75199.1,
RC ECO:0000313|Proteomes:UP000198662};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FNGF01000009; SDL75199.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9MLW2; -.
DR STRING; 380244.SAMN05216298_5055; -.
DR OrthoDB; 9806127at2; -.
DR Proteomes; UP000198662; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd07346; ABC_6TM_exporters; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF644; OS07G0464600 PROTEIN; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..320
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 351..585
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 608 AA; 64300 MW; 16E4E130A3D2467F CRC64;
MTTTVSERPA AGQLPVAGTP AVRRAFLRLL MSEKRRALAA VGLHLVAAVA AAVAPLLLGE
MLDELAAGKG TGVVDRLALG LIASIVAVVA FTWLGTFVSH RLGEKLSARM RVEFVDRALR
LPMPVVEQAG SGDLMTRSSA DVPEAGVLFR DGLPQIIVSV LKVVVFLAAM LWASPVLGLC
MLVVAPGLVI GTRWYLKRAR DGYLNERQAE SGIGDTIGAS ADGARTTETY RLRAQRDGAG
DDTVARHWRA ARYTLYLRSV FFPFLDGSYA LPTAAVLLVG GALYFDGSIT LGTVAACAVL
TRQIMFPIDH ILMWVEKVQR GFAAMSRIEG VAEAEDTGAA ATAELPADGT VDLADVRYAY
PSGVRDVLHG VSLSVPAGQR LAVVGPSGAG KSTLARLVSG SDSPREGRAT IGGVDVAALP
LDERRRRVTL VTQEHHVFTA SLRDNLILAK AEATDQELRD ALTAVGADWA ADLPDGLDTA
LGGKARELDA ASAQQIALAR IILADPDVVI LDEATAMLDP RAARDTERAL GAVLEGRTVI
AIAHRLHTAH DADRIAVVED GRVAELGSHD ELIALDGHYA GLWRAWHGEP EGLKAADEDH
YAAAGNPV
//
