ID A0A1G9MYU9_9ACTN Unreviewed; 487 AA.
AC A0A1G9MYU9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SDL79304.1};
GN ORFNames=SAMN05444921_101370 {ECO:0000313|EMBL:SDL79304.1};
OS Streptomyces wuyuanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1196353 {ECO:0000313|EMBL:SDL79304.1, ECO:0000313|Proteomes:UP000199063};
RN [1] {ECO:0000313|Proteomes:UP000199063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7042 {ECO:0000313|Proteomes:UP000199063};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; FNHI01000001; SDL79304.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9MYU9; -.
DR STRING; 1196353.SAMN05444921_101370; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000199063; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199063};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 50125 MW; 52C51CED8A421526 CRC64;
MTQSSVEPRT TAEDAGPGSR VPAGRSWLDR YFHISERGST VAREVRGGIT TFMAMAYILL
LNPLILNGKD VAGNVLSQPG LITATAFAAA ATTLLMGFVG KVPLALAAGL SVSGVLASQV
VPQMTWPQAM AMCVMYGVVI CLLVVTGLRE LIMNSIPLAL KHGITMGIGL FIALIGLVKA
GFVGKGSEFG PPVTLGAGGE LAGWPVLIFC LTLLLIFMLQ ARAIPGAILI GIVVGTVVAV
AVHSIAGLDA KAWNMSPPEL SRGAVSMPDF SLFGHVEFGG WGEVGAITVG FIVFTLVLAG
FFDAMATIIG VGTEAKLADE RGRMPGLSKA LFIDGAGGAI GGVSGGSGQT VFVESATGVG
EGARTGLASV VTGLFFAACL FFTPLTAIVP PQVASAALVV IGAMMMQNAK HVDWGDRSVA
IPVFLTVVLM PFTYSITPGV AAGVISYVAI KAAQGKAREV GGFMWALTAI FIVFFALNPI
EGWLGVH
//
