ID   A0A1G9QEL2_9GAMM        Unreviewed;       505 AA.
AC   A0A1G9QEL2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:SDM08917.1};
GN   ORFNames=SAMN05661010_03328 {ECO:0000313|EMBL:SDM08917.1};
OS   Halomonas muralis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=119000 {ECO:0000313|EMBL:SDM08917.1, ECO:0000313|Proteomes:UP000198654};
RN   [1] {ECO:0000313|EMBL:SDM08917.1, ECO:0000313|Proteomes:UP000198654}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14789 {ECO:0000313|EMBL:SDM08917.1,
RC   ECO:0000313|Proteomes:UP000198654};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNGI01000011; SDM08917.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G9QEL2; -.
DR   STRING; 119000.SAMN05661010_03328; -.
DR   OrthoDB; 5389341at2; -.
DR   Proteomes; UP000198654; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1040.50; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198654}.
FT   DOMAIN          7..184
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          188..285
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   DOMAIN          413..496
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   505 AA;  54035 MW;  5355F1BF28600E83 CRC64;
     MSHTITTIGI VGTGAMGRGI AQVAAEAGLR VKLHDAREGA LDEARAFIAK LWDRGVAKQR
     FSQSRADALA ARFEEAATLN ELADCELVIE AIVERIDAKQ KLFQQLEAVI GERAILATNT
     SSLSVTEIAA ACSRPERVIG LHFFNPVPLM KVVEVIPGLR TDAAVIEATE ALGQRFGHFT
     ARATDTPGFL VNHAGRAFGT EALRALAEGV ADHVTIDRLL KDQGGFRMGP FTLLDLTGLD
     VSHAVMESIY HQYYQEPRFR PSALTGQRLA AGLLGRKSGE GFYRYVDGQA VVPDEPAAPR
     ATPMPVWISA EDADAQRALA DLVETAGWPL ETGATPSETA LCLLTPYGED ATDCALRQGL
     DPARCVAVDM LAGLDRRRCL MTSPATRGDV RDAAHALLAA DGTPVSAIHD SGGFVLQRVV
     ACIVNVGADI AQQRVAEPAT IDRAVELGLG YARGPLAMGD HYGAKRILSI LENLQAASGD
     PRYRPSPWLR RRARLGLPLT ATDAQ
//