ID A0A1G9T0C4_9ACTN Unreviewed; 482 AA.
AC A0A1G9T0C4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Aerobic C4-dicarboxylate transport protein {ECO:0000313|EMBL:SDM41066.1};
GN ORFNames=SAMN04487981_101425 {ECO:0000313|EMBL:SDM41066.1};
OS Streptomyces sp. cf386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1761904 {ECO:0000313|EMBL:SDM41066.1, ECO:0000313|Proteomes:UP000198720};
RN [1] {ECO:0000313|Proteomes:UP000198720}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF386 {ECO:0000313|Proteomes:UP000198720};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FNHV01000001; SDM41066.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9T0C4; -.
DR STRING; 1761904.SAMN04487981_101425; -.
DR OrthoDB; 9766690at2; -.
DR Proteomes; UP000198720; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198720};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 434..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..460
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 482 AA; 50193 MW; 6D19AC1967EFC99C CRC64;
MPPSVPSLPR RVARMLRTSL FAQVACALVL GIVVGKLWPG FGADLQPLGD GFIRLIKTII
SPLVFCVVVV GIAKAGDLKA FGRIGLKALI WFEVASTLAL LIGLLAANLV QPGSGMNVDP
STLDASAVDA KTGGGHLPST TEFALNALPT SFIGAFAENS LLQVLVLACL VGAALLHLGH
TKVPQVLPAI EQAQEIIFAI VGFVMRLAPI AVFGAMAVLI GNYGLGVIET YGKLIILCYA
AAALFIALLA VALKVVTGLS LWKFLRYIRE EMLLALGTAS TESVLPRVMQ KLRKAGARDD
AVGLVLPTGY SFNLDGASLY LSIGTLFIAQ AVGVDLSLGQ QVTVILVLML TSKGMAGIPG
SAFLALSATA SSLGAIPAGA VALLLGVDRI MDSMRVVTNL LGNCVAVFAV SRWEGALDKE
WARKVLDGEI VVELDDEESE KAEPGKAEKA ELKKPETSEA SESGEPVAVP AQTDKETASG
AS
//
