ID A0A1G9U4A8_9FIRM Unreviewed; 442 AA.
AC A0A1G9U4A8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SDM54819.1};
GN ORFNames=SAMN05660299_01109 {ECO:0000313|EMBL:SDM54819.1};
OS Megasphaera paucivorans.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Megasphaera.
OX NCBI_TaxID=349095 {ECO:0000313|EMBL:SDM54819.1, ECO:0000313|Proteomes:UP000199309};
RN [1] {ECO:0000313|EMBL:SDM54819.1, ECO:0000313|Proteomes:UP000199309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16981 {ECO:0000313|EMBL:SDM54819.1,
RC ECO:0000313|Proteomes:UP000199309};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; FNHQ01000008; SDM54819.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9U4A8; -.
DR STRING; 349095.SAMN05660299_01109; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000199309; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199309};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 442 AA; 46971 MW; 9E8C251A909E126A CRC64;
MYSYIQRICE QQFQLKAWGT SVSTEIIAGM TTFATMAYVL AVVPKMMGEA GLPAGEILTA
MVMMIFFTTL AMGLYTNRPF ALAPGMGGVA IFSITLVQLQ HVSVGIASAI VFLSGCLFLI
VTVLGIREAI VMVIPKGIKI SISAGVGMFL AVIGLRNAKV LAANASKVAL SLGDISQPVV
VLAAMGLFVL LALEARKVRG AALISIVIAT IIGIPLGVTK IPAAIFAVPS GINEVFFNFD
LMGALDVRYI PYLFVFFLPD FFSSFGTAIG IGGKAGFLDK NGDLPDLNKI FQVDSIAATL
GSFFTIPVLI TYLESGAGVE AGGRTGLTAV TTAVMFLLVL AITPAALMIP AAATAPVLLY
VGVSMMAGMR NLDYSDMAEY VPAFLCIAFT AFTFNIANGI SLAFLAYVII KLASRRYREM
TWGHYLLALL LLYYFYSMAG VK
//
