ID A0A1G9UHC5_9ACTN Unreviewed; 1211 AA.
AC A0A1G9UHC5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ATP-binding cassette, subfamily C, CydCD {ECO:0000313|EMBL:SDM59337.1};
GN ORFNames=SAMN05444921_110159 {ECO:0000313|EMBL:SDM59337.1};
OS Streptomyces wuyuanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1196353 {ECO:0000313|EMBL:SDM59337.1, ECO:0000313|Proteomes:UP000199063};
RN [1] {ECO:0000313|Proteomes:UP000199063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7042 {ECO:0000313|Proteomes:UP000199063};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FNHI01000010; SDM59337.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9UHC5; -.
DR STRING; 1196353.SAMN05444921_110159; -.
DR Proteomes; UP000199063; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR GO; GO:0042883; P:cysteine transport; IEA:InterPro.
DR GO; GO:0034775; P:glutathione transmembrane transport; IEA:InterPro.
DR CDD; cd18584; ABC_6TM_AarD_CydD; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR014223; ABC_CydC/D.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR014216; ABC_transptr_CydD.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR NCBIfam; TIGR02868; CydC; 1.
DR NCBIfam; TIGR02857; CydD; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF261; ATP-BINDING_PERMEASE PROTEIN CYDD; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SDM59337.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199063};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 751..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 779..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 854..882
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 894..915
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..306
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 338..578
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 637..920
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 956..1189
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 558..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1211 AA; 127151 MW; 028924E8C6877AA3 CRC64;
MFHVKPVDPR LLRYARATRL FMAAVVALGL AGAALVVAQA MLIAEVVVGA FQRGLDAGEL
WTPLVLLAAV AAGRGLVAWL TELAAHRASA AVKSELRLRL LERAAQLGPG WLSGQRSGSL
AALATRGVDA LDDYFARYLP QLGLAVVVPV AVLARIVTED WVSAAVIVVT LPLIPIFMVL
IGWATEARMN RQWTLLSRLS GHFLDVVAGL PTLKVFGRAK AQAEAIRKIT SEYRRATVKT
LRIAFLSSFA LELLSTLSVA LVAVGIGMRL VHGDLDLYTG LVVLILAPEA YLPLRQVGAQ
YHAAAEGLSA AEEIFRVLET PVRAGGTASV PAARGVRLEL DSVTVRHEGR GVPSLEAASL
TVEAGETVAL VGPSGVGKST LLDAVLGFVA PDEGTVRVGA PGRKPVDLTS LDRADWHRHI
AWVPQRPYLF AGTIAENVRI ARHGADDAEV LAALREADAQ DFVAALPQGV ETVLGEDGAG
LSAGQRQRIA LARAFLADRP LLLLDEPTAA LDGETEAGVV DAVRRLARGR TVLLVVHRPA
LLSVADRVVE LRPAQRVPAG EEPGGRLVPS GVPRPSPSAD GMLSTADAYA AAEPVEQPAR
SDSDLVPGTV QGASGQDHGR VLARVRGMAG ALRGRLVLAL VLGSLALGSA VGLMAVSGWL
ISRASEQPPV LYLMVAVTAT RAFGIGRAVF RYAERLVSHD AVLRMLADLR VGVYRRLERI
APAGLRRTRR GDLLSRLVAD VDALQDYWLR WTLPAGAALV VGAASVGFTA WLLPEAGAVL
AVGLLAAGVA VPLLSGAVAR RAERRLAPAR GALAAQVVDL LRGTGELTVT GALARRTAAV
READRALTRI ASRAAAATAL GGGLSAVACG LTVVFVAYAG VMAVHSGRVE GVELAVVVLT
PLAAFEAVVG LPLAVQYRQR VKRSAQRVFE VLDAPVPVSE PVEPAPAPAS AFPLEVRGLS
VRHFGARQDA LSGFDLTLTA GRRVAVVGAS GSGKTTLAQA LLRFLDVRSG TYTVGGTDAT
ALDGDTVRRC VGLCAQDAHL FDSSIRENLR LARTGASEEE LRAALAAARL LDWTDGLPDG
LDTLVGEHGA QLSGGQRQRL ALARALLADF PVLLLDEPAE HLDLATADAL TADLLAATEG
RTTVLITHRL RGLDAVDEVV VLDEGRTVQR GPYAELAAMD GPLRRMLERE HAGDLLGSGS
GSRLSMTNRT N
//
