ID A0A1G9V1E8_9ACTN Unreviewed; 438 AA.
AC A0A1G9V1E8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=SAMN05660642_03037 {ECO:0000313|EMBL:SDM65816.1};
OS Geodermatophilus siccatus.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Geodermatophilus.
OX NCBI_TaxID=1137991 {ECO:0000313|EMBL:SDM65816.1, ECO:0000313|Proteomes:UP000198680};
RN [1] {ECO:0000313|EMBL:SDM65816.1, ECO:0000313|Proteomes:UP000198680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45419 {ECO:0000313|EMBL:SDM65816.1,
RC ECO:0000313|Proteomes:UP000198680};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016, ECO:0000256|RuleBase:RU000416}.
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DR EMBL; FNHE01000007; SDM65816.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G9V1E8; -.
DR STRING; 1137991.SAMN05660642_03037; -.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000198680; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR031303; C5_meth_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00675; dcm; 1.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00095; C5_MTASE_2; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 94
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 438 AA; 48036 MW; 1ADB4687D4DCCC81 CRC64;
MEPPLPTSTI SPEPHPRVTH EVVEICAGAG GQAIGLERAG FGHALAVELD GYACETLRQN
RPQWKVRQGD VADRGLWTPA DYEGVALLAG GVPCPPFSIA GKQLGASDER DLFAWAVELC
VTEVKPRALM LENVRGLSMP RFAAYRQHVL DRLASAGYVG DWRLLHASDF GFAQLRPRFV
LVALKEEDAP YFRWPEPTPS PQTVGETLRD LMGANGWPHV DDWVKLANDI APTLVGGSKK
HGGADLGPTR AKRAWRELGV DALGVANEAP GPDSPHPDVK LPKLTVPMVA RLQGFDEARG
WRLAGRKTAQ YRQVGNAFPP PVAEEVGRSI IRALEHADEP HDMPELASAT MHDPVYRVLR
EADGYLTPSA ILSKLTVPYD AIQLERRIAH LSKDFIIELQ ETTSGPAYKL GEFKAFVGQD
DHDRHEAFAH RAGRSRIS
//
