ID   A0A1G9VWM1_9ACTN        Unreviewed;       342 AA.
AC   A0A1G9VWM1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Fatty acid desaturase {ECO:0000313|EMBL:SDM76590.1};
GN   ORFNames=SAMN04487981_102510 {ECO:0000313|EMBL:SDM76590.1};
OS   Streptomyces sp. cf386.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1761904 {ECO:0000313|EMBL:SDM76590.1, ECO:0000313|Proteomes:UP000198720};
RN   [1] {ECO:0000313|Proteomes:UP000198720}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF386 {ECO:0000313|Proteomes:UP000198720};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00009295}.
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DR   EMBL; FNHV01000002; SDM76590.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G9VWM1; -.
DR   STRING; 1761904.SAMN04487981_102510; -.
DR   OrthoDB; 104711at2; -.
DR   Proteomes; UP000198720; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR   CDD; cd03506; Delta6-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR19353:SF19; DELTA(5) FATTY ACID DESATURASE C-RELATED; 1.
DR   PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
DR   PIRSF; PIRSF015921; FA_sphinglp_des; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198720};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        217..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          58..314
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   342 AA;  37753 MW;  544DE7AD0D039BC4 CRC64;
     MIRPPPSETS GSDFARLSRK IADAGLLGRR PGYYALRITV VAGLYVSGWV AVALVGDSWW
     TLAVAAFLAV VFGQVALLAH DAAHRQVFRR RRASEVSGRI AGAGIGMGYG WWHDKHTRHH
     ANPNHEELDP DLDPDLLVWS QDQARAAKGL PRLIGRWQAF LFFPLLTLEG FNLHVSSVKA
     LANRSLKHRT LDGALLFAHF AAYLAVLLWL LPPGMAIAFL AVHQCLFGVY LGSLFAPNHK
     GMPILTGEDR PDFLRRQVLT SRNVRGGRFT DIALGGLNHQ IEHHLFPSMP SPNLPKARTI
     VRRHCQDLGL DYVETGLITS YRLALASLHQ AGAPLRHARV PA
//