ID   A0A1G9ZEW1_9ACTN        Unreviewed;       186 AA.
AC   A0A1G9ZEW1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Formate dehydrogenase major subunit {ECO:0000313|EMBL:SDN19677.1};
GN   ORFNames=SAMN05660642_04313 {ECO:0000313|EMBL:SDN19677.1};
OS   Geodermatophilus siccatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=1137991 {ECO:0000313|EMBL:SDN19677.1, ECO:0000313|Proteomes:UP000198680};
RN   [1] {ECO:0000313|EMBL:SDN19677.1, ECO:0000313|Proteomes:UP000198680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45419 {ECO:0000313|EMBL:SDN19677.1,
RC   ECO:0000313|Proteomes:UP000198680};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; FNHE01000013; SDN19677.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G9ZEW1; -.
DR   STRING; 1137991.SAMN05660642_04313; -.
DR   OrthoDB; 7376058at2; -.
DR   Proteomes; UP000198680; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 2.20.25.90; ADC-like domains; 1.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   PANTHER; PTHR43598:SF1; FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, MAJOR SUBUNIT; 1.
DR   PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00022485};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          42..98
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
SQ   SEQUENCE   186 AA;  20645 MW;  2725B0F3660F4AC2 CRC64;
     MKTWLDAWPV FRQLTGPDPL GRGAAARSKA TENVVSRTAT ADRVVQSVCP YCAVGCGQRI
     YVKDEQIVQI EGDPDSPISR GRLCPKGSAS KQLVTSPTRV TTVKYRRPFG TEWEDLDLDT
     AMHMIADRVL EARRKGWQDD NDGKRVNRTM GIASLGGATL DNEENYLMKK LYSAMGAIQI
     ENQARI
//