ID A0A1H0A2U9_9ACTO Unreviewed; 605 AA.
AC A0A1H0A2U9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=SAMN04487766_12110 {ECO:0000313|EMBL:SDN27016.1};
OS Actinomyces ruminicola.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=332524 {ECO:0000313|EMBL:SDN27016.1, ECO:0000313|Proteomes:UP000199671};
RN [1] {ECO:0000313|EMBL:SDN27016.1, ECO:0000313|Proteomes:UP000199671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KPR-7B {ECO:0000313|EMBL:SDN27016.1,
RC ECO:0000313|Proteomes:UP000199671};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
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DR EMBL; FNHU01000021; SDN27016.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0A2U9; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000199671; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154}.
FT DOMAIN 14..180
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 201..280
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 282..596
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 605 AA; 67763 MW; E35DE6292BCBBD76 CRC64;
MLSVRNSASR AVVSLDGVWR FQLDPEDRGQ AERWFATPLP APRPMPVPAS YNDITIAPEV
HDHVGPAWYE REAVAPHNLG EDRLVLRFGS VTHEARVWVD GVEVAQHTGG YLPFEADITD
HVTAGRDFRI TVRVDNRLSW QSIPVGFLAE DAQGRTVQRY FHDFFNYAGI HRSVVLYTRP
WIAVTDVTIV TDYATGPEGT AGRVTYTVEA EGAEHVHVVV KDAAGAEVAH AKGAAGTLTI
DNVNLWQPGS GYLYTLEVHA RGSADGGASE DVYPQRFGVR TVTVRDSQFL INGEPFYFRG
YGRHEDNLVR GKGHDPALMV HDFELMEWQG ANSFRTSHYP YAEEVMDYAD ERGFVVIDET
AAVGLNTAII GGFFGGDPIP LFSEDHVNAH TQAAHADHIR ELIARDKNHP CVVLWSLANE
PESNTEASLR YFEPLAAAAR EADPTRPVGY VNVMMGQPAQ ERVVDLFDVV MLNRYYGWYV
NNGDLPAAEA GLRAEIDAWI ERAPGKPILF TEYGADTLSG MRDLLRRPWS EEFQVDLLAM
YHRVFDAYPQ IVGEQMWNFA DFQTGTGTTR VGGNKKGMFT RSREPKQNAF VVRDRWLGKR
RRHEC
//
