ID   A0A1H0ATG5_9ACTN        Unreviewed;       761 AA.
AC   A0A1H0ATG5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=DNA helicase IV {ECO:0000313|EMBL:SDN36625.1};
GN   ORFNames=SAMN05444921_12536 {ECO:0000313|EMBL:SDN36625.1};
OS   Streptomyces wuyuanensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1196353 {ECO:0000313|EMBL:SDN36625.1, ECO:0000313|Proteomes:UP000199063};
RN   [1] {ECO:0000313|Proteomes:UP000199063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.7042 {ECO:0000313|Proteomes:UP000199063};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNHI01000025; SDN36625.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0ATG5; -.
DR   STRING; 1196353.SAMN05444921_12536; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000199063; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000199063}.
FT   DOMAIN          224..612
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   REGION          506..532
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         245..252
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   761 AA;  83743 MW;  EC2CB6372627C0F7 CRC64;
     MAAQEAAVDS VRDREILVEQ DHLDQVYRRL EEKIHEAEFL MDDAAKRGQV GTPGALAERD
     AQVFRAGIHL NRLNSEFEDF LFGRIDLLLG KDGKKGPDGA YTSVEPAEDA VRTDETGQYA
     DIAETLHIGR IGVLDSDYAP LVIDWRAPAA APFYRSTPVD PGRVVRRRVI RSKGRRVLGV
     EDDLMRPELT ARLGGAMLPV IGDGALMAAL GQARTHTMRD IVSSIQAEQD LVIRAPAASV
     TEVSGGPGTG KTAVALHRAA YLLYQDRRRY AGGILVVSPT PLLVAYTEGV LPSLGEEGQV
     AIRAVGSLVD GAEATTYDDP AVARVKGSLR MLKVLRKAAR GALELGDTPA RLRVVAFGRR
     LELENDELRR IRHNVLGGTA PVNLLRPRAR RLLLDALYAK SGAAGRHTDP ELAAELRSSF
     DDDVSSEDSF IDFLDAWWPE LNPRGVLAAM ADERRLGRWA RRVLNPGEVR RLARSLRRDG
     LSVHDVAVLD ELQAILGVPV RPRKKREAHP LDQLTGLEEL MPQREESQRE RAERLAAERT
     EYAHVIVDEA QDLTPMQWRM VGRRGRHATW TIVGDPAQSS WSDPDEAAEA RDDALGTRPR
     RRFELTVNYR NPSEVAELAA RVLTLAMPGM VAPRAVRSTG LRPRFAVARD DLERTVRQET
     QRLLDEVDGT VGVVVAMDRR EEAARWLDGL GDRAVALGSL EAKGLEYDAT VVVSPAEIAD
     ESPAGLRVLY VALTRATQQL TVVSGRRDEP DADGVPDLLR D
//