ID   A0A1H0AY30_9EURY        Unreviewed;       583 AA.
AC   A0A1H0AY30;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=tRNA-archaeosine synthase {ECO:0000313|EMBL:SDN38299.1};
GN   ORFNames=SAMN05192554_13120 {ECO:0000313|EMBL:SDN38299.1};
OS   Haloarchaeobius iranensis.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halorubellaceae; Haloarchaeobius.
OX   NCBI_TaxID=996166 {ECO:0000313|EMBL:SDN38299.1, ECO:0000313|Proteomes:UP000199370};
RN   [1] {ECO:0000313|EMBL:SDN38299.1, ECO:0000313|Proteomes:UP000199370}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EB21,IBRC-M 10013,KCTC 4048
RC   {ECO:0000313|Proteomes:UP000199370};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: tRNA modification; archaeosine-tRNA biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005030}.
CC   -!- SIMILARITY: Belongs to the archaeosine synthase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008906}.
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DR   EMBL; FNIA01000031; SDN38299.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0AY30; -.
DR   STRING; 996166.SAMN05192554_13120; -.
DR   OrthoDB; 115061at2157; -.
DR   UniPathway; UPA00393; -.
DR   Proteomes; UP000199370; Unassembled WGS sequence.
DR   GO; GO:0016763; F:pentosyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR   CDD; cd21149; PUA_archaeosine_TGT; 1.
DR   Gene3D; 3.10.450.90; ArcTGT, C2 domain; 1.
DR   Gene3D; 2.30.130.10; PUA domain; 1.
DR   Gene3D; 3.20.20.105; Queuine tRNA-ribosyltransferase-like; 1.
DR   Gene3D; 3.40.50.10630; Uracil-DNA glycosylase-like; 1.
DR   InterPro; IPR040777; DUF5591.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR036511; TGT-like_sf.
DR   InterPro; IPR029402; TGT_C2.
DR   InterPro; IPR038250; TGT_C2_sf.
DR   InterPro; IPR002616; tRNA_ribo_trans-like.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   InterPro; IPR036895; Uracil-DNA_glycosylase-like_sf.
DR   NCBIfam; NF040592; tRNA_mod_ArcS; 1.
DR   NCBIfam; TIGR00451; unchar_dom_2; 1.
DR   PANTHER; PTHR46499:SF2; ARCHAEOSINE SYNTHASE; 1.
DR   PANTHER; PTHR46499; QUEUINE TRNA-RIBOSYLTRANSFERASE; 1.
DR   Pfam; PF17884; DUF5591; 1.
DR   Pfam; PF01472; PUA; 1.
DR   Pfam; PF01702; TGT; 1.
DR   Pfam; PF14810; TGT_C2; 1.
DR   SUPFAM; SSF88802; Pre-PUA domain; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF51713; tRNA-guanine transglycosylase; 1.
DR   SUPFAM; SSF52141; Uracil-DNA glycosylase-like; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199370};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          92..239
FT                   /note="tRNA-guanine(15) transglycosylase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01702"
FT   DOMAIN          283..432
FT                   /note="DUF5591"
FT                   /evidence="ECO:0000259|Pfam:PF17884"
FT   DOMAIN          446..512
FT                   /note="tRNA-guanine transglycosylase patch-forming"
FT                   /evidence="ECO:0000259|Pfam:PF14810"
FT   DOMAIN          526..580
FT                   /note="PUA"
FT                   /evidence="ECO:0000259|Pfam:PF01472"
FT   COILED          204..231
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   583 AA;  64668 MW;  0BDB5B4BC10374EA CRC64;
     MTDYFEVLER DGAARLAELR LTEPVTTPAL VDDHVDDAGS LWRAERELPD GDESRLTVLP
     HRGLPAGTAD EVADSFAVDY PTVDYPSAAV VSADTAADHG ADAYVVSDAS GSLGHGAGMR
     DLVLAVREAI PDDTGLYLSG VATPRNVATL AYAGVDLFDT SRAYVRGTEG RYLTTDDAYF
     LEDLDEFPCA CPACAKPREE FGREDCAAHN VNALEAELRR VRRRIRDGRL RDYIEGQARQ
     DQWLTALMRE LDQQYGYLEE RTPVYRGADL DAATEDTIRR AEIQRFAERV TTRYRSRFDD
     HPLVLVPCSA AKPYSESQSH RQYMDAIQFR GHIVSMTSPI GVVPQELETT YPAQHYDSVV
     TGRWNADEVE FVSEVLRRYL ERSDYPRIVA HVPDDYRPII ERIEDDLDAP VEYTVADHPT
     TSESLGNLRD ALAGESAYSK REREHNTVRA LADVQLGDGA GDELFESFRT TSRYPKLQVR
     DDDGEQLATQ VPSYGTLAFT LEGARRWDES DAPTKRVEID GFVPHGSVLA PGVVDADEDI
     RVGDEVVVEG PAAYAIGRAQ MHGAAMVEST RGEAASVRHV EEM
//