ID   A0A1H0BKL5_9ACTN        Unreviewed;       423 AA.
AC   A0A1H0BKL5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Biotin carboxylase {ECO:0000313|EMBL:SDN46194.1};
GN   ORFNames=SAMN05444921_127106 {ECO:0000313|EMBL:SDN46194.1};
OS   Streptomyces wuyuanensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1196353 {ECO:0000313|EMBL:SDN46194.1, ECO:0000313|Proteomes:UP000199063};
RN   [1] {ECO:0000313|Proteomes:UP000199063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.7042 {ECO:0000313|Proteomes:UP000199063};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNHI01000027; SDN46194.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0BKL5; -.
DR   STRING; 1196353.SAMN05444921_127106; -.
DR   OrthoDB; 6964321at2; -.
DR   Proteomes; UP000199063; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.40.50.20; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR   InterPro; IPR040570; LAL_C2.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   PANTHER; PTHR43055; FORMATE-DEPENDENT PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; 1.
DR   PANTHER; PTHR43055:SF1; FORMATE-DEPENDENT PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; 1.
DR   Pfam; PF02786; CPSase_L_D2; 1.
DR   Pfam; PF18603; LAL_C2; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199063}.
FT   DOMAIN          110..303
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   REGION          397..423
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  45366 MW;  F1A2063F8805B95D CRC64;
     MTKPHILVLG GGEDQLPAYH EARRLGYGVV GVDQRPDALG ASAADLFLCM TTRDPERIAA
     MVGHLDIAAV ISPASDAAQE SVAELSRLLR TPHQPAPDAV RASVDKGYFH EVLERLGLPT
     YAYIQSADPV ELRLAAAALP LPVIVKPSDS SGSKGVQVVA DQAALPEAVA EAQRYSFSGE
     VIVEEMLLGR HLSAEAFLRD AKLATIAVTE RSTTGAPRMI TTGHMVPAEL APATEIALRS
     MVMDVCGALG HTDGPVNFDF VVDRTEEIRF IEMGARLGGN GMPLLVRHAY GIDTYEAALR
     LALGLPFELQ ARHDKKTALQ ILTTDTDGIL RTVEGADEVR ALPQTAELRL FAGPGSRVRR
     YTQAGHKLGY LLLVADSYGE LREAQARARS LLRFGVEPDT PPAPAPAQAD AAPIRTDLLT
     EKR
//