ID   A0A1H0BR14_9ACTN        Unreviewed;       576 AA.
AC   A0A1H0BR14;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Copper transport protein {ECO:0000313|EMBL:SDN48094.1};
GN   ORFNames=SAMN05660199_00092 {ECO:0000313|EMBL:SDN48094.1};
OS   Klenkia soli.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Klenkia.
OX   NCBI_TaxID=1052260 {ECO:0000313|EMBL:SDN48094.1, ECO:0000313|Proteomes:UP000199088};
RN   [1] {ECO:0000313|EMBL:SDN48094.1, ECO:0000313|Proteomes:UP000199088}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45843 {ECO:0000313|EMBL:SDN48094.1,
RC   ECO:0000313|Proteomes:UP000199088};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FNIR01000001; SDN48094.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0BR14; -.
DR   STRING; 1052260.SAMN05660199_00092; -.
DR   OrthoDB; 5242236at2; -.
DR   Proteomes; UP000199088; Unassembled WGS sequence.
DR   GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR   GO; GO:0046688; P:response to copper ion; IEA:InterPro.
DR   Gene3D; 2.60.40.1220; -; 1.
DR   InterPro; IPR032694; CopC/D.
DR   InterPro; IPR007348; CopC_dom.
DR   InterPro; IPR008457; Cu-R_CopD_dom.
DR   InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR   PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR   Pfam; PF04234; CopC; 1.
DR   Pfam; PF05425; CopD; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..576
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011696098"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        180..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        222..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        257..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        331..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        437..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          25..118
FT                   /note="CopC"
FT                   /evidence="ECO:0000259|Pfam:PF04234"
FT   DOMAIN          323..454
FT                   /note="Copper resistance protein D"
FT                   /evidence="ECO:0000259|Pfam:PF05425"
SQ   SEQUENCE   576 AA;  57975 MW;  3EB90A7910BFF65B CRC64;
     MRRVLLVLLS GVGLLLVGAG PASAHATLVT SSPSDGARLD TAPAEVTLQF DENVSLGAGY
     ARVLGAGGDR VDTGGAAVTD DILTIPLRGD LPDASYVVTW RVVSADSHPV SGAYAFVVGD
     GELTPATDVE AGSGVDPVVG ALLPVARWLG YAGLALGVGI PVFLALCWPA GWASRRAQRY
     VVVGLGAVGV GGLLSFLLQG PYAAAVGVAG LVDPQLLGTT LASTYGVTLL VRVGLVAALA
     ALVALRPPRS APGTPWLVAG GVLGLGLVVS TAATGHPVAG SLPGLAVVVT SVHVAAMTVW
     LGGLVVLLAV VLRPGTPAGE LATALPRYSR LAAGSVAALV VTGVVQSVRE VGSPEALVST
     TYGWVLVAKL VLVLALLAVA GVSRVWVQQR LGAPRPGRRR VVAHAFSAEQ SSAEEVDAAA
     QRSEAVVSDT APFRRSVLLE VAVAAVVLAL SAVLVGTPPA KAAVAQPVDV TLPLQSATGT
     DGSVQLSLDP ARPGANVLHV YLLDATGQLA QPQSLRVTLT EADQQIGPLD VALQPAGPGH
     SIGDAAIPTA GTWTVTVSVR LDEFTALTAS TTFPVR
//