ID   A0A1H0C575_9ACTN        Unreviewed;      1312 AA.
AC   A0A1H0C575;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Alpha-1,2-mannosidase, putative {ECO:0000313|EMBL:SDN53025.1};
GN   ORFNames=SAMN05216259_104425 {ECO:0000313|EMBL:SDN53025.1};
OS   Actinacidiphila guanduensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310781 {ECO:0000313|EMBL:SDN53025.1, ECO:0000313|Proteomes:UP000199341};
RN   [1] {ECO:0000313|EMBL:SDN53025.1, ECO:0000313|Proteomes:UP000199341}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2022 {ECO:0000313|EMBL:SDN53025.1,
RC   ECO:0000313|Proteomes:UP000199341};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNIE01000004; SDN53025.1; -; Genomic_DNA.
DR   STRING; 310781.SAMN05216259_104425; -.
DR   OrthoDB; 9804511at2; -.
DR   Proteomes; UP000199341; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR   Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR005887; GH92_a_mannosidase_put.
DR   InterPro; IPR041371; GH92_N.
DR   InterPro; IPR012939; Glyco_hydro_92.
DR   NCBIfam; TIGR01180; aman2_put; 1.
DR   PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR   PANTHER; PTHR12143:SF43; PUTATIVE SUBFAMILY (AFU_ORTHOLOGUE AFUA_6G13760)-RELATED; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF07971; Glyco_hydro_92; 1.
DR   Pfam; PF17678; Glyco_hydro_92N; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199341};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           34..1312
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011667339"
FT   DOMAIN          77..221
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   REGION          96..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          147..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1156..1191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        160..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1312 AA;  140076 MW;  228E4473AB7F5FD5 CRC64;
     MRSGRPRRLL ARPLLAAAVS VALTVPLSAV AHAATGTAGQ GHAPAPAFST SFEDGQAQPA
     ADTAETLGDG KPWVSGVTAG TLPVLPGSIK DKITAVTANS DNPPNETAQK AADEDPNTKW
     LTFNSTGWLQ YRLSGDVTVK KYALTSANDS PGRDPKDFQL QGSQDGSHWT TVDSRTGQDF
     PGRFKSHVYD VANPGAYSYY RLNVSLNHGD PIVQLADLIL SDGSTGPAPA AGMTTEVGTG
     PSSGPNVTPN VGFTGLKALE YAGTHTADGA VHAYNKLYDV HIKVARDTQL SYDIFPELTG
     GDLAYPSTYA AIDLHFTDGT YLSQSRNPAD DQNGVPLTPR EQGDSKILYA SQWNAQSADI
     GKVAAGKTID RILLGYDNPK GSAAEGAQTQ FKGWIDDLAI GSAPAADPHA TYADHVDTRR
     GTNASGSFSR GNNLPATAVP NGFNFYTPVT DAGSDSWEYS YAAQNNADNL PTLQALGISH
     EPSPWMGDRD LFQVMPSAAT GTPSLDRAKR ALPFKHSDET AKPQYYGVTF TDGIKAEIAP
     ADHSADFRFT FTGDTGDLLF DNIDNNGGLT FDPADGTLQG WAEHKSGLST GASRMFVYAE
     FDQKPTTAQK VTGYGRDNVT GYAQFDTSKS KTVTMRIATS FISVDQAKKN LSLEIPQGTS
     FGTVEKRAAQ QWNAKLGKVE VQGASSDQLT TLYSDLYRMN LYPNNGSENT GTAAHPVWQY
     ASAYQPQGTS TATQTGAKVV DGKVYVNNGF WDTYRSEWPA YSLLESKTAG QLVNGFVQQY
     KDGGWTARWS SPGYADLMTG TSSDVAFADA YAKGVTGFDA QAAYEAAVKN ATVVPTNSGV
     GRKGLSTSEF TGYTDTSVDG SISWSLDGYV NDYGIGTMAA KLAKDPKTPK ADRERYKEES
     AYFLARAQDY TEVFNKNTGF FEGRNPDGSW RVPDSSYDPQ TWGYEYTESN GWNYAFTVPQ
     DPAGLASIYG GQKNLEKKLD TFFSTQETAD GDTGSYGGTI HEMIEARDVR MGELGMSNQP
     SYAIPYMYDY AGAPAKTQAV VRQIEQRLYT GSSIGEGYPG DEDNGAASTW QIFGALGFYP
     LQVGSDNYVI GSPLFTKATI HLDNGRSIVV NAPGNSGKNV YVQSLKVNGK PYDKVYLTQD
     QLSAGAVLDF TMGSQPSSWG TGKDALPTSL TPKGGTPSPL TDTTGSGLGT ATASDGTATA
     ALFDNTSATQ ATFTTATPQI TYTYSGSGQK ATFYTLTSGR TAGQDPTAWR LEGSTDGTHW
     KTVDSRTGQS FDNRLQTRPF EIAHPGTYTS YRLVVTAGSG DTTTLAEVEL LH
//