ID   A0A1H0CUE4_9ACTN        Unreviewed;       440 AA.
AC   A0A1H0CUE4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=HNH endonuclease {ECO:0000313|EMBL:SDN61484.1};
GN   ORFNames=SAMN05192576_2533 {ECO:0000313|EMBL:SDN61484.1};
OS   Nocardioides szechwanensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=1005944 {ECO:0000313|EMBL:SDN61484.1, ECO:0000313|Proteomes:UP000199004};
RN   [1] {ECO:0000313|EMBL:SDN61484.1, ECO:0000313|Proteomes:UP000199004}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.11147 {ECO:0000313|EMBL:SDN61484.1,
RC   ECO:0000313|Proteomes:UP000199004};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNIC01000003; SDN61484.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0CUE4; -.
DR   STRING; 1005944.SAMN05192576_2533; -.
DR   OrthoDB; 3776577at2; -.
DR   Proteomes; UP000199004; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00085; HNHc; 1.
DR   Gene3D; 1.10.30.50; -; 1.
DR   InterPro; IPR002711; HNH.
DR   InterPro; IPR003615; HNH_nuc.
DR   Pfam; PF01844; HNH; 1.
DR   SMART; SM00507; HNHc; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|EMBL:SDN61484.1};
KW   Hydrolase {ECO:0000313|EMBL:SDN61484.1};
KW   Nuclease {ECO:0000313|EMBL:SDN61484.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199004}.
FT   DOMAIN          350..402
FT                   /note="HNH nuclease"
FT                   /evidence="ECO:0000259|SMART:SM00507"
FT   REGION          60..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   440 AA;  48477 MW;  2C73AFE648F7B21E CRC64;
     MSITRLDKNR PDAGELEDTT AAELIARVRD ARATADRAEV DLLRLAVAWA HSHPLVPGDA
     SWHAPAASGD EDGSPSDTDD VEDLEWFGIP DVAWDAPAAF AAANAMTTTA GKAFLRDALI
     LRHRLPGVFA CVVSHQVPVW RARRIAQAVI GKPADVAAYV DTELARTAHA VGTVTLDRVL
     DQAMTFLYPE QREEEQLEAL DARYARLSER SLNHTGVAEM ALRAEWADLK DFDKALSLVA
     AALKRDGNTE PLDVRRAMAI GVLADPARAL ALINGEEPPA PTREVVAYVH LTEEAVRGLD
     PLARDEHGRT WLEATFRAWC LRTDRHVTVR PVIDLNDSHP GCEGYTPSES LRERVILRNP
     TCVFPHCARP SRACDLDHLI PWLEGGPTTE ANLAPLCRHH HRLKTHAGWR YQSLAPGTFL
     WHEPHGQWLI TAPTGTVDIT
//