ID A0A1H0DE55_9BACI Unreviewed; 684 AA.
AC A0A1H0DE55;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05443253_11653 {ECO:0000313|EMBL:SDN68241.1};
OS Bacillus sp. OK048.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1882761 {ECO:0000313|EMBL:SDN68241.1, ECO:0000313|Proteomes:UP000199133};
RN [1] {ECO:0000313|EMBL:SDN68241.1, ECO:0000313|Proteomes:UP000199133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK048 {ECO:0000313|EMBL:SDN68241.1,
RC ECO:0000313|Proteomes:UP000199133};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNHN01000016; SDN68241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0DE55; -.
DR STRING; 1882761.SAMN05443253_11653; -.
DR OrthoDB; 9759607at2; -.
DR Proteomes; UP000199133; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000199133};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 19..136
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 174..222
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 476..679
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT MOD_RES 68
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 684 AA; 77819 MW; D82F67F950214CF2 CRC64;
MDPKGSIVNL SSTPTQKVNI LMVDDHPENL LALEAVLTSP NYNLISAHSG KEALKCMLQH
DFAVILLDVQ MPGLNGFDTA KLIKAREKTK NIPIIFITAI SQDMEHVHQG YSVGAIDYIF
KPFQPETLKK KIEQFVKIHQ IHKETIIQTD LGHLLELNKV NKKLDRTTLN LRRTEALSRA
ISETITDTIV TFDHQGSILS VNPAARSMFG YQAKELLEQH ILKLFPEWED EVLCDSSLSL
SLLLQSTLRQ SVGKIIEVVA RRKDNSCFYA DLLIASTIIE DEQIFVCTIR DVTERKQIEE
VKRQRFTNLE QIVEERTLEL TNSNIKLQKE IDERKRMADH LFHTQERFRK IFESSPCLMA
ILSQRDLTFM EVNTSWTNYI GYSCDELIHQ RINCKHFINE ANETIIDLTK KIRNKKIRYE
TKNGEFRSGL LSTELIDIQS EPCMLVVLTD ITDRVHLENE MYRLDRLNLI GEMAAGIAHE
IRNPMTTVQG FLQLSRNKVD NLSTDIVDLM LEELYRANSI ITEFLNLAKN KISVKKKQNL
NAIIEALSPL IQAEAFRSNK QMKLELGECP DISLDEKEIR QLILNIALNG LDAMTSNGSL
TIKTYKDKET VVLQIKDEGQ GISPEVLSKL GTPFFTTKET GTGLGLAICY SVAKRHDAQI
EIETSEKGTT FSARFQLIPS LTNA
//
