ID A0A1H0DI49_9BACI Unreviewed; 257 AA.
AC A0A1H0DI49;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=DNA-binding transcriptional regulator, IclR family {ECO:0000313|EMBL:SDN69691.1};
GN ORFNames=SAMN05216498_2879 {ECO:0000313|EMBL:SDN69691.1};
OS Tenuibacillus multivorans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Tenuibacillus.
OX NCBI_TaxID=237069 {ECO:0000313|EMBL:SDN69691.1, ECO:0000313|Proteomes:UP000199334};
RN [1] {ECO:0000313|EMBL:SDN69691.1, ECO:0000313|Proteomes:UP000199334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.3442 {ECO:0000313|EMBL:SDN69691.1,
RC ECO:0000313|Proteomes:UP000199334};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNIG01000007; SDN69691.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0DI49; -.
DR STRING; 237069.SAMN05216498_2879; -.
DR OrthoDB; 9791752at2; -.
DR Proteomes; UP000199334; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:SDN69691.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..65
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 66..249
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 257 AA; 29038 MW; 9844A20336102680 CRC64;
MNQSVLKALQ LLDLFDEQHP ELTLKEISEL SRLPKPTAYR LLQALEMRGF LMKTDEQDPR
YRLGLKLLGL GQLVSDQLDL RQMARPLMEG LAYTINEAVH LVVVDGHQAT YIEKVDSQRA
LRLFTKVGQS VPLFIGSGPK LLLAYMPEEE RLEVLEKHDM YSMTEEKPID KATLWDELVM
IRQKGYALSI SEQDLDTTGI SFPILDYQGQ VLAALTVSGL SSRFEGDNLT FINKETKIAA
NEISKRLGYS TAKKGVH
//
