ID A0A1H0E488_9ACTN Unreviewed; 1032 AA.
AC A0A1H0E488;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Peptide/nickel transport system substrate-binding protein {ECO:0000313|EMBL:SDN77113.1};
GN ORFNames=SAMN05216259_105463 {ECO:0000313|EMBL:SDN77113.1};
OS Actinacidiphila guanduensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=310781 {ECO:0000313|EMBL:SDN77113.1, ECO:0000313|Proteomes:UP000199341};
RN [1] {ECO:0000313|EMBL:SDN77113.1, ECO:0000313|Proteomes:UP000199341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.2022 {ECO:0000313|EMBL:SDN77113.1,
RC ECO:0000313|Proteomes:UP000199341};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC {ECO:0000256|ARBA:ARBA00005695}.
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DR EMBL; FNIE01000005; SDN77113.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0E488; -.
DR STRING; 310781.SAMN05216259_105463; -.
DR OrthoDB; 5240629at2; -.
DR Proteomes; UP000199341; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd08506; PBP2_clavulanate_OppA2; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR039424; SBP_5.
DR InterPro; IPR000914; SBP_5_dom.
DR PANTHER; PTHR30290:SF88; OLIGOPEPTIDE-BINDING PROTEIN APPA; 1.
DR PANTHER; PTHR30290; PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00496; SBP_bac_5; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000199341}.
FT DOMAIN 10..275
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 294..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..345
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..415
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1032 AA; 108220 MW; 79E1C8F491D6AC4B CRC64;
MSDGLFAGRY DLAELLGSGG MARVHKARDT RMGRTVAIKT LLADLAQDPD ARRRFAREAH
AAGALNHPGI VTVHDQDEVH DGDTIVPFLV MEYVSGRTLA QLVREQAPLD PARAVRITCD
ILDALAHAHA HGTVHRDVKP ANVMITDAGH LKVTDFGIAR VLDTDTRLTT AGSSIGTPSY
MSPEQINGGD VDARSDIYAV GCVLTELLTG HPPFHDGNPL NLMYRHVHTA PPAPSAANPR
VPAQLDALVL AALAKDPGER PADAGVFRSS LWAWLTATDA RTLTGPAAVL PAEPADRLPL
GKQTPAADPR ATYGVGTALP SLPAQPAAPE SPAQPAPPVP SIPSASSAPS APAAPSTAPP
PSAYAHPGPY APQHTPPPNG PRAPEHPAYS RSPHVPLPPP YQPATPPPVN LGHAAAVPPV
PPARGWSTRR KVLTGVAGVA VAGITVSVVL ATGALSGGGH PHHDPTPGPT HAVSDALARH
GGVAGSGYNG GVNGVVRASS RKGGTVRIAA AYLDTSMLDP ADTYNTSDWN IQRLLLRKLV
DYAPAPGDKG RKLLPDLATN TGEVGPDGLT WTYHLKSGLR FQDGSPITSK DIKYGVERTF
DRSVHPGGPS YFPDLLDEGQ NYPGPYKDPD PSKLGLHSVT TPDDSTIVFK LAKPDSDFPY
ILAMSIGAPV PQAADTDGGR GFETHLVASG PYEVGSYDPG KSLHLVRNPE WSQATDPIRT
QLPYAFDVKV YATQDEVEQA LLDGNADLDF AASLLSSGTQ QEIVDDPRKK ADTDAAYSGA
TRFLSLQTDV APFSNADCRK AVEFAVDRSA VRTALGGQYA GGDVATTMLP PTDDSYDPSA
APYTGHDGTP DIAAAKTHLA ACGKPGGFSV TLASVSSTTS RSDAAVEAIA DSLARAGITV
KLKKLSATDF YDTLLDPAKL KKSGWGIAYT SWAADWPTGG GFLRELVEPG GAANYPGLRD
TQLTGMVDQA DDQTSPAAAA QEWTKIDARL MQDAVYVPLV YDRHLVYRGP HLTNVYQHQV
IGGIDLSALG AA
//
