ID A0A1H0G0U0_9GAMM Unreviewed; 1032 AA.
AC A0A1H0G0U0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=FAD/FMN-containing dehydrogenase {ECO:0000313|EMBL:SDO00517.1};
GN ORFNames=SAMN04487951_11138 {ECO:0000313|EMBL:SDO00517.1};
OS Halomonas arcis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=416873 {ECO:0000313|EMBL:SDO00517.1, ECO:0000313|Proteomes:UP000199677};
RN [1] {ECO:0000313|Proteomes:UP000199677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.6494 {ECO:0000313|Proteomes:UP000199677};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; FNII01000011; SDO00517.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0G0U0; -.
DR STRING; 416873.SAMN04487951_11138; -.
DR OrthoDB; 9811557at2; -.
DR Proteomes; UP000199677; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199677}.
FT DOMAIN 52..284
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 1032 AA; 113903 MW; 0B57B88EBB3664BE CRC64;
MIASLDSRTA PFERLGTHYV RFLEALKTRG FEGEIAPDYA NRTVLATDNS IYQRLPQAAV
FPKHAEDLER LAKLAGEVPH RDIVLTPRGG GTGTNGQSLT DGIVVDVSRH MNQIVEIDVE
HRRVRVQAGV VKDQLNAALK PHGLFFAPEL STSNRATIGG MIATDASGQG SCEYGKTRDH
VLALDTILLG GKHLHSHPLS ADEEHQACQQ DGIVGRVHTT AADIIDQQRE LIDATFPPLN
RCLTGYDLAH LRDDSGQLNL NSLLCGAEGS LGFLNEAVLN VLPIPKHSTL VNVRYAGFME
ALRDAKALMA SSARPTSIET IDDTVLQLAM EDFVWDSVAE FFPAGDTPIR GINLIEFNDD
DPDALAERVR AFTDHLSQDA TVERLGYTLA EGRPQIQKVY GMRKRSVGLL GNVQGEKRPL
PFVEDTAVPP EHLADYIAEF RAALDARGLS YGMFGHVDAG VLHVRPALDM KDPAQEALIR
EISDEVAALT QRYGGLLWGE HGKGVRSEYG PQFFGKLYPS LQRVKAAFDP YNQLNPGKIA
SPSDKGELIA REHDPELLTI DGVPMRGQFD RTIDERAWQA YDAAVYCNGN GACYNYDVDD
PMCPSWKATR DRRHSPKGRA SLIREWLRLQ SKAGIDVVEE SRKKKAEGGW GFIKSFPLRL
ANTLSRKQHH DYSHEVYDAM AGCLACKSCA GQCPVKVNVP QFRSQFLEVY HGRYLRPLRD
YVVGGTEFML PAFAKITPAY NAIMGQPWVE QLMRKVVGIS DSPALSRANL KKKLRAWGVA
EATPTSLALL TEQQRANSVI IVQDAFTSHF EAKLVMDIVE LLSRLNLRVF VMPFSANGKP
LHVQGFLGAF ERTAQKQAQR LRTLAHFDIP LVGIDPAMTL TYRQEYVKAL GGKAVPEVLM
LQEWLATRLN TLAVRPLELS DPGYKLLSHC TESTNAPGSP KAWQQVFAAF GLELELVSTG
CCGMSGTYGH ETRNVATSRT IYAQSWQPQV EANENAGKLL ATGYSCRSQV KRYSGEVLPH
PLQALLTALK RS
//
