ID   A0A1H0GGQ4_9ACTN        Unreviewed;       364 AA.
AC   A0A1H0GGQ4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=O-methyltransferase {ECO:0000313|EMBL:SDO06086.1};
GN   ORFNames=SAMN05216259_107118 {ECO:0000313|EMBL:SDO06086.1};
OS   Actinacidiphila guanduensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310781 {ECO:0000313|EMBL:SDO06086.1, ECO:0000313|Proteomes:UP000199341};
RN   [1] {ECO:0000313|EMBL:SDO06086.1, ECO:0000313|Proteomes:UP000199341}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2022 {ECO:0000313|EMBL:SDO06086.1,
RC   ECO:0000313|Proteomes:UP000199341};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNIE01000007; SDO06086.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0GGQ4; -.
DR   STRING; 310781.SAMN05216259_107118; -.
DR   OrthoDB; 3862772at2; -.
DR   Proteomes; UP000199341; Unassembled WGS sequence.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.1350; -; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR   PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   PIRSF; PIRSF005739; O-mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SDO06086.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199341};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000313|EMBL:SDO06086.1}.
FT   DOMAIN          136..342
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   364 AA;  38654 MW;  7D26AF7ECE3BD3D1 CRC64;
     MTAPARTSPA TATATAPLST PPPPEAAAAP SASMRLRELA FGAAAAAAVR AACRLGLPDA
     LGDEPRSAED LAARLDLPAQ PLRRLLRALA CHEVFAEQPD GRFAHTPMSR LLRQDEPGSL
     HHIALWCTEP WTWDAWPRLE DAVRTGRDVF GDLYGKGFFA HLHEDAPESA RVFDRAMTSS
     SRQAARDLAA YVDLTGVRSV ADIGGGQGLA LAELLEKEPA LHGTLLDLPA VVAGADPRLR
     PGGALADRAD LVAGDCREAI PVAADLYVLK NILEWDDAST RATLRNVVAA AEPGARVLVI
     ENLVDDSPSM RFTTAMDLLL LLNVGGAKHT RASMTHLMEE AGLPVSSVAP INPYLDAFES
     RTPA
//