ID A0A1H0GJA1_9BACI Unreviewed; 1457 AA.
AC A0A1H0GJA1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:SDO06910.1};
GN ORFNames=SAMN04488053_106130 {ECO:0000313|EMBL:SDO06910.1};
OS Alkalicoccus daliensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Alkalicoccus.
OX NCBI_TaxID=745820 {ECO:0000313|EMBL:SDO06910.1, ECO:0000313|Proteomes:UP000198778};
RN [1] {ECO:0000313|Proteomes:UP000198778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10369 {ECO:0000313|Proteomes:UP000198778};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
CC {ECO:0000256|ARBA:ARBA00010860}.
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DR EMBL; FNIL01000006; SDO06910.1; -; Genomic_DNA.
DR STRING; 745820.SAMN04488053_106130; -.
DR OrthoDB; 363232at2; -.
DR Proteomes; UP000198778; Unassembled WGS sequence.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 1.
DR Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 8.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR InterPro; IPR002477; Peptidoglycan-bd-like.
DR InterPro; IPR036365; PGBD-like_sf.
DR InterPro; IPR036366; PGBDSf.
DR InterPro; IPR003646; SH3-like_bac-type.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 1.
DR Pfam; PF01471; PG_binding_1; 8.
DR Pfam; PF08239; SH3_3; 3.
DR SMART; SM00646; Ami_3; 1.
DR SMART; SM00287; SH3b; 3.
DR SUPFAM; SSF47090; PGBD-like; 8.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51781; SH3B; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000198778};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..1457
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011724780"
FT DOMAIN 1058..1120
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 1128..1190
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 1199..1270
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT REGION 240..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..309
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..330
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..345
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..408
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1457 AA; 158125 MW; 6CF486BE7785EC87 CRC64;
MKKHRLKQAG ITGLASLLFL SSALPATAGS MEDLYEDLFP ELSDEESSLE VSPSLFNQSF
EEALHISYEE GIEDVSLGLF EEESGTLLGE LEVTPIDATK AAWEFQVTQE DVTEEVILED
QRYFIEVLTD EEAEEEIETA QVSFVHYSEL PVLSWEESEE LEELELGGQA YSALQEFGLD
PGELSLSFEA EGLEEAEEVS IEEDGSFNVD VSFLSETTSL YFTLADPLGN TLEEEKLVTI
EEDTDTSFEE ENADADESTL ENEEDASPAE EEITEAKESE ETALEEETEK KEESSNEEET
DVSEENTSTE EVVNEEKNED VSEEEELTSE ETTEKEKSTE KSSNEEETDV SEENTSTEDV
VNEEKNEDVS EEEELTSKET TEKEKSTEKS STEEETDVSE ENTSTEDIVN EENTDAAKST
AENEEAVNET TASEETEETF STFSTFSMQA TEAPAEEYYD GASGEYIREL KFDLTALGFG
NFPSYPSTRF GPVTMGVVED FQRAYGLPVT GIPDQATLDA IENALNEETK ETISSFSTQA
TKASEGEFYD GASGEYIREL KLDLTALGFG NFPSYPSTRF GPVTMGVVED FQKANGLNIT
GIPDSITLKT IDSALNSNFY SGATGDYVTD LKINLTKLGF GNFPESPSSL FGPVTMSVVE
DFQKAHGLAV TGIPDAATLD AMNVALSTTF YNGASGEYVR NLKLDLTKLG FGSFPESPSS
LFGPVTMSVV EDFQKAHGLA VTGIPDAATL DAMNVALSTT FYNGASGEYV RNLKLDLTKL
GFGSFPESPS SLFGPVTMRV VEDFQKAKGL AATGIPDTAT LQAMDLALKT AFYNGASGEH
VRTLKLDLTK LGYGSFPSSP SAAFGNVTMK VVEDFQKANN LKVTGIPDSA TLKSINDQLE
ILANTTYEPG SSGVHVQELK KKLTLLGFGS FPSNPSIYYG SVTKKVVEEF QKYYGVKVTG
IGDKSTFNKI EELFKSPLSP GNSNTQTVEL KNNLTKLGYG SFPTNPSRVY GSVTSSVVKD
FQKKNSLAIN GIADGPTLQK INSQLNNQPK EEIKPVVIET GEVTATALNI RSGPGTSHDR
VGTLTNGTVV EILGEESGWY LIKFDGGTAY ASGSFIDTTK KEAAPKVIDT GKVTATTLNI
RSGPGTSHDR VGTLTNGTVV EILGEENGWY LIKFDGGTAY ASGSFIDTSK LPAPGNDFTG
SSIIAYTNGS SLNVRSGPST AYRVLDNLGS NTRVEIISTR ASSGSDTWHQ IRYDGGKTGF
VSAGYLQLAT KASARTGPLA GKKIVLDAGH GGHDSGGIGG GMLEKDVVLD ITNRAEELLR
AAGAEVIMLR RTDFFLALGQ RSFMANRSGA DVFLSIHTNM FNGQARGTET FWHDRYERSN
SIRLANAVQD ATVAKMGTHY RRVDYGNYSV IRQTEIPSAL LEIGFKDHPD DAAKLRSNTY
RQRAAEAIRD GMINYFK
//
