ID   A0A1H0GRD3_9GAMM        Unreviewed;       325 AA.
AC   A0A1H0GRD3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=2-oxoisovalerate dehydrogenase E1 component beta subunit {ECO:0000313|EMBL:SDO09463.1};
GN   ORFNames=SAMN04487957_103313 {ECO:0000313|EMBL:SDO09463.1};
OS   Halomonas shengliensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=419597 {ECO:0000313|EMBL:SDO09463.1, ECO:0000313|Proteomes:UP000199075};
RN   [1] {ECO:0000313|Proteomes:UP000199075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.6444 {ECO:0000313|Proteomes:UP000199075};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR   EMBL; FNIV01000003; SDO09463.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0GRD3; -.
DR   STRING; 419597.SAMN04487957_103313; -.
DR   OrthoDB; 9780894at2; -.
DR   Proteomes; UP000199075; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT   DOMAIN          4..180
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   325 AA;  35535 MW;  EB2590B59B7D0183 CRC64;
     MPTMNMLQAI NQALDIAMTE DDKVVCFGED VGLFGGVFRA TSHLQEKYGR ARCFNTPLVE
     QGILGFANGL AAQGSVPVAE IQFADYIFPA FDQIVNETAK FRYRSGDLFN VGGLTIRAPY
     GGGISGGLYH SQSPEAYFAH TPGLKIAVPR NPYQAKGLLL AAIRDPDPVL FFEPKRLYRA
     STGEVPEEDY QLPLGEAEVT REGTDVTVLG WGAQMEVIDR AVELAEKEGI SCEVIDLRSI
     LPWDEESVVE SVLKTGRLVI THEAPLTGGF AGEIAATVQE RCFLYLESPI ARVTGLDTPF
     PLTLEKEYLP DHLKVFEAIK ASVAF
//