ID A0A1H0HCF4_9ACTN Unreviewed; 534 AA.
AC A0A1H0HCF4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=4-hydroxyphenylacetate 3-monooxygenase oxygenase component {ECO:0000313|EMBL:SDO16827.1};
GN ORFNames=SAMN05428965_2980 {ECO:0000313|EMBL:SDO16827.1};
OS Geodermatophilus sp. DSM 45219.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Geodermatophilus.
OX NCBI_TaxID=1881103 {ECO:0000313|EMBL:SDO16827.1, ECO:0000313|Proteomes:UP000198730};
RN [1] {ECO:0000313|EMBL:SDO16827.1, ECO:0000313|Proteomes:UP000198730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45219 {ECO:0000313|EMBL:SDO16827.1,
RC ECO:0000313|Proteomes:UP000198730};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNIQ01000004; SDO16827.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0HCF4; -.
DR STRING; 1881103.SAMN05428965_2980; -.
DR Proteomes; UP000198730; Unassembled WGS sequence.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR024677; HpaB/PvcC.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF500125; 4_HPA_large; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:SDO16827.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 32..296
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 304..504
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 172..174
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 213
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 534 AA; 59915 MW; C8193FA1A07DD48D CRC64;
MTLEQEREVV GPTSAADGVP DLDAPTATRP MTGDEYIESL RDDREVWIYG ERVEDVTTHP
AFRNPIRMTA RLYDSMHDPA VKDKVTTPTD TGSGGVTHPF FRAPHSVEDM VADREAIATW
ARMSYGWMGR APDYKAAFLG TLGANSEFYA PYEDNAKRWY KESQEKVLYW NHAIINPPVD
RNLPPDEVGD VFMKVEKETD AGLIVSGAKV VATGSAITNY NFIAHYGLPI KKKEYSLICT
VPMDAPGVKL ICRASYTQQA AVMGSPFDYP LSSRMDENDT IFIFDKVLVP WENVFLYGDV
EKINGFFPAS GFLPRFTLHG CTRLAVKLDF IAGLLLKALE ITGSKDFRGV QTRVGEVIGW
RNIFWALSDA MIHNPDEWVG GTMLPKLDYG LTYRMFMIQG YPRVKEIIES DVASGLIYLN
SHSLDFKTPE IRPYLDKYVR GSNGIEAVDR VKLMKALWDS VGTEFGGRHE LYERNYSGNH
EGVKAELLFA AEAQGTTGAM KGLAEQCLSE YDLDGWTVPD LIGNDDVSYF RNRR
//
