ID   A0A1H0HSM8_9ACTN        Unreviewed;       650 AA.
AC   A0A1H0HSM8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=FAD-NAD(P)-binding {ECO:0000313|EMBL:SDO22215.1};
GN   ORFNames=SAMN04487981_109131 {ECO:0000313|EMBL:SDO22215.1};
OS   Streptomyces sp. cf386.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1761904 {ECO:0000313|EMBL:SDO22215.1, ECO:0000313|Proteomes:UP000198720};
RN   [1] {ECO:0000313|Proteomes:UP000198720}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF386 {ECO:0000313|Proteomes:UP000198720};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNHV01000009; SDO22215.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0HSM8; -.
DR   STRING; 1761904.SAMN04487981_109131; -.
DR   OrthoDB; 3653265at2; -.
DR   Proteomes; UP000198720; Unassembled WGS sequence.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR038732; HpyO/CreE_NAD-binding.
DR   PANTHER; PTHR40254; BLR0577 PROTEIN; 1.
DR   PANTHER; PTHR40254:SF1; BLR0577 PROTEIN; 1.
DR   Pfam; PF13454; NAD_binding_9; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198720}.
FT   DOMAIN          28..190
FT                   /note="FAD-dependent urate hydroxylase HpyO/Asp
FT                   monooxygenase CreE-like FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF13454"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   650 AA;  70463 MW;  69B0F7C59ECCD4A0 CRC64;
     MRPTRPGVTP LTAPTSAPTP ESPTVSIALV GAGPRGTSVL ERLCASTPEL LPPGARLTVH
     VIDPAPPGPG RVWRTAQSAE LLMNTVSSQV TLFTDDSVDC SGPIRSGPSL YDWAAGALGP
     DEYPTRAHYG RYLEWVFAKV VREAPPALRI ETYAARAIRL DDAPDGRQVL TLDDGRTLPG
     LSAVVLAQGH LPTAADTTQR HVAAYAERHG LHHVPPANPA DVDLSSISPG EPLLLRGLGL
     NFFDHMALLT TGRGGVFVPA PEGLTGLRYV PSGNEPRLYA GSRRGIPYQA RGDNAKGPYG
     RHLPLVLTSE VIAGFRKRAD SGEAPDFLAE IWPLVAKEVE TVYYTALIPE ARRRSDFTER
     FLAVPHRHPQ EACLLDEFGV AEDERWSWDR VSRPYTGGGF ADPGQWSDWL RAYLREDAAQ
     AARGNVDGPL KSALDVLRDL RNELRLIVDH GGLTGASRRD HLDRWYTPLN AFLSIGPPRR
     RVEELVALME AGVVEVLGPR LEVREEDGAW VAHSPEVPGS AVRVTALVEA RLPEPDLRRS
     ADDLLARLLK TGQCRPHTVD GYETGGLDVT QRPYRLIDRQ GRAHPRRFAF GVPTEGVHWV
     TAAGARPGVD SVTLSDADAV ARAALRAGAA GADGEYEVEL WPNVELASID
//