ID A0A1H0JSS2_9BACI Unreviewed; 506 AA.
AC A0A1H0JSS2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=4,4'-diaponeurosporene oxygenase {ECO:0000256|ARBA:ARBA00039159};
DE AltName: Full=4,4'-diaponeurosporene oxidase {ECO:0000256|ARBA:ARBA00041900};
DE AltName: Full=Carotenoid oxidase {ECO:0000256|ARBA:ARBA00042619};
GN ORFNames=SAMN04488053_11474 {ECO:0000313|EMBL:SDO46600.1};
OS Alkalicoccus daliensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Alkalicoccus.
OX NCBI_TaxID=745820 {ECO:0000313|EMBL:SDO46600.1, ECO:0000313|Proteomes:UP000198778};
RN [1] {ECO:0000313|Proteomes:UP000198778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10369 {ECO:0000313|Proteomes:UP000198778};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 AH2 + all-trans-4,4'-diaponeurosporene + 2 O2 = 4,4'-
CC diaponeurosporenal + 2 A + 3 H2O; Xref=Rhea:RHEA:56104,
CC ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:17499, ChEBI:CHEBI:62743, ChEBI:CHEBI:79065;
CC Evidence={ECO:0000256|ARBA:ARBA00035945};
CC -!- PATHWAY: Carotenoid biosynthesis; staphyloxanthin biosynthesis;
CC staphyloxanthin from farnesyl diphosphate: step 3/5.
CC {ECO:0000256|ARBA:ARBA00037901}.
CC -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC CrtP subfamily. {ECO:0000256|ARBA:ARBA00038194}.
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DR EMBL; FNIL01000014; SDO46600.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0JSS2; -.
DR STRING; 745820.SAMN04488053_11474; -.
DR OrthoDB; 9814556at2; -.
DR Proteomes; UP000198778; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR014105; Carotenoid/retinoid_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR NCBIfam; TIGR02734; crtI_fam; 1.
DR PANTHER; PTHR43734:SF7; 4,4'-DIAPONEUROSPORENE OXYGENASE; 1.
DR PANTHER; PTHR43734; PHYTOENE DESATURASE; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Carotenoid biosynthesis {ECO:0000256|ARBA:ARBA00022746,
KW ECO:0000256|RuleBase:RU362075};
KW Oxidoreductase {ECO:0000256|RuleBase:RU362075};
KW Reference proteome {ECO:0000313|Proteomes:UP000198778}.
FT DOMAIN 14..491
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 506 AA; 56711 MW; C9957C389EF6AB26 CRC64;
MTAKQKAVVV GAGLGGLSAA MRLAGDGYEV TVLEKNETIG GKLNQRSGKG FTFDTGPSIL
TMPWVLEKLF QSVHRNINDY MDIVRIEPQW RTFYEDGTSI DVLSDIPGML EEMRKVKAEP
GKSFMKFLSY SQDMYDLCMK SFYKTSIGGL KDLRQQHTLK ELLSMDPFHT VADSTKKHFD
NKYLEQLFNF FVMYVGSNPY QSPAILNQLV YVQLGLGIHY VKGGMYNIAR GMKTVLDELR
VDVLVNSPVS HIYIKEDKAQ GVVTESGDFY EADIVVSNLE AIPAYKQLLP KTGKTKKEIK
TLTKNFAPTV SGQVLLLGVN KKFTELEHHN FFFSEDPEKE FKQIFEKGVP ADDPTIYIGV
SSKTDPSQAP EGKENLFVLT HVPPKTALKK KVDWDKYREV ILDKLERMGM EGLRDSIEFE
YEFTPDTIEE LYGSHGGSIY GIAADKATNG GFKIPARSQV YENLYFSGGA THPGGGVPMV
TLSGQLTADL IKEDREKKEL KTKKAK
//
