ID   A0A1H0MCK8_9ACTN        Unreviewed;      1052 AA.
AC   A0A1H0MCK8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Type 2 lantibiotic biosynthesis protein LanM {ECO:0000313|EMBL:SDO78107.1};
GN   ORFNames=SAMN05216259_112155 {ECO:0000313|EMBL:SDO78107.1};
OS   Actinacidiphila guanduensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310781 {ECO:0000313|EMBL:SDO78107.1, ECO:0000313|Proteomes:UP000199341};
RN   [1] {ECO:0000313|EMBL:SDO78107.1, ECO:0000313|Proteomes:UP000199341}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2022 {ECO:0000313|EMBL:SDO78107.1,
RC   ECO:0000313|Proteomes:UP000199341};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNIE01000012; SDO78107.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0MCK8; -.
DR   STRING; 310781.SAMN05216259_112155; -.
DR   OrthoDB; 9148343at2; -.
DR   Proteomes; UP000199341; Unassembled WGS sequence.
DR   GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR   CDD; cd04792; LanM-like; 1.
DR   Gene3D; 1.50.10.20; -; 1.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR025410; Lant_dehyd.
DR   InterPro; IPR017146; Lanti_2_LanM.
DR   NCBIfam; TIGR03897; lanti_2_LanM; 1.
DR   Pfam; PF13575; DUF4135; 1.
DR   Pfam; PF05147; LANC_like; 1.
DR   PIRSF; PIRSF037228; Lant_mod_RumM; 1.
DR   PRINTS; PR01950; LANCSUPER.
DR   SMART; SM01260; LANC_like; 1.
DR   SUPFAM; SSF158745; LanC-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199341}.
FT   DOMAIN          200..568
FT                   /note="Lantibiotic biosynthesis protein dehydration"
FT                   /evidence="ECO:0000259|Pfam:PF13575"
FT   REGION          1012..1052
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1026..1052
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1052 AA;  109679 MW;  834567FD96C63C10 CRC64;
     MMDPQTWWVG GVALAERLPP PPTPAGTADP ARTWQSAYSS PALLRTRLAD TGLDEEGLSA
     LLAEEPAALA GRIGRPAWVA TVEDALARAP LDPPLPAVGS WSAGFAAVLA PFTEAAAERL
     LMTIGRRGTD GPADLAAVRD CFTDRLGRAL VQLARRTLVL ELNVLRERGQ LRGDTAELRF
     CDFVRQASAR SALRALVTEY PVLARLLAQC CDQAVNAWNE LLGRFADDRA DVVEKLLAGV
     DPGRLVQVDT SAGDRHQGGR AVAVLSFEHG AKVVFKPRPL SVHEHFNDAC GWLNSHLAGL
     DLRRLAVLGR PGYGWVEYAP AAPCAGPADV QRFYWRLGAL LALIHALGAT DMHFENLVAS
     ADQPVLVDLE TLFHPELHRH ACADPAQAAL TASVARTALL PLFLVGEHGA LDISGLGGDR
     DTPLPEEVTG WSAPGTDTMR LVRTVGMFRG SANRPRLRDA EADPSLHVEP LVAGFRAGYD
     AIAGHRTELI GPGGLLARFT RDVTRAVLRP TRWYANLLDE STHPDVLREA LDRERLFDVL
     WRDSAGGQGL RTLSGAELAE LWAGDVPVAV CSPGATDLAI GPLTVDGLVA ECGLARAEHR
     VAMMGDTDRF DQEWVIRATL ATRRRGNGPR TSAAPPGQPA ATVPDAERML FAACGIADRI
     LARAQDDGRR VNWLCLEPLD DRIWAVRPQG AGLPHGYCGT ALFLAQLADL TGTERYTSVA
     RRALAPLPDL LASLAGRPAD LHAVGAGFAG LGGIAYALTL LAGLLDDTEV AGWAATAVDL
     AAAATAAAGA DAQPGVLDGD AGCLAAMLAV QQATGSATAA RTARACADRL AAQAPGGLPA
     GGFSTGAAGV GWALLRFAAA GGGPGHASAG LATLRTAAAR CATAPVGTGW CDEASGAALA
     IADSGPAADV PELTGLLNDV VERSAAPTAG DHSLCHGEAG ALDLLLAATG PGSAGPGAAL
     PRAAALLSAL DRFGPRCGTP DSVSSPGLLT GLAGIGHELL RLGFGPRVPS VLLLQSPAPH
     PPTPTPRRRT SDERQPPRQR LEEPGRPRRG RL
//