ID   A0A1H0MGR2_9ACTN        Unreviewed;       579 AA.
AC   A0A1H0MGR2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=N-terminal domain of peptidoglycan hydrolase CwlO-containing protein {ECO:0000313|EMBL:SDO79466.1};
GN   ORFNames=SAMN05660199_02627 {ECO:0000313|EMBL:SDO79466.1};
OS   Klenkia soli.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Klenkia.
OX   NCBI_TaxID=1052260 {ECO:0000313|EMBL:SDO79466.1, ECO:0000313|Proteomes:UP000199088};
RN   [1] {ECO:0000313|EMBL:SDO79466.1, ECO:0000313|Proteomes:UP000199088}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45843 {ECO:0000313|EMBL:SDO79466.1,
RC   ECO:0000313|Proteomes:UP000199088};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C40 family.
CC       {ECO:0000256|ARBA:ARBA00007074}.
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DR   EMBL; FNIR01000007; SDO79466.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0MGR2; -.
DR   STRING; 1052260.SAMN05660199_02627; -.
DR   OrthoDB; 1099523at2; -.
DR   Proteomes; UP000199088; Unassembled WGS sequence.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd14814; Peptidase_M15; 1.
DR   Gene3D; 3.30.1380.10; -; 1.
DR   Gene3D; 6.10.250.3150; -; 1.
DR   Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR   InterPro; IPR009045; Hedgehog_sig/DD-Pept_Zn-bd_sf.
DR   InterPro; IPR000064; NLP_P60_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR003709; Pept_M15B.
DR   PANTHER; PTHR47053; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   PANTHER; PTHR47053:SF1; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   Pfam; PF00877; NLPC_P60; 1.
DR   Pfam; PF02557; VanY; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF55166; Hedgehog/DD-peptidase; 1.
DR   PROSITE; PS51935; NLPC_P60; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:SDO79466.1}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..35
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           36..579
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011770584"
FT   DOMAIN          293..417
FT                   /note="NlpC/P60"
FT                   /evidence="ECO:0000259|PROSITE:PS51935"
FT   COILED          67..94
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   579 AA;  57477 MW;  7B1E8B2CF2793B82 CRC64;
     MRSRVGSSGA VLVGAVLVGA VLSVALVAVP GTASAAPSDQ PGGTTGILDS AELTALQDQA
     ADVQGDLQER QAAVTAAQDR LAQAQQAADA AAAEVTDAGT TLAQEQAVVS RYASAVYRDG
     GAPSALSLLL AGGDPGDVVS ALGYLDVIDS GTDALLQAAE DRRQQALAQQ ASADTALADS
     QAEADAVAAQ VGDLEAAAAA VTDQLDEALG AVDRQLAQLQ AEQVQVNQQT AAAWQGYVAS
     LAAAGITPPP AAALRDPTAG VPGGLVPVGG SAGTAQAGAA QLPRQPASLL VLPAETIAAV
     SAAMTDLGLP FAPGTAGPDS YDCGSLVQTV YGAAGIALPA TQGDLYATTS PVAAADVLPG
     DLVFLGTAES GLSHVGIALD PQTMLAADGR AGAVVVRGLP ADQVLGIGRP SVAPRAAVPV
     PGPTGGALAV ECGNTVYPST YDGSRSWGGY PNGLIPPSAL CPLGVAGHAL RCDAAAAYRA
     MSAAFAGAFG PALCITDSYR SYASQVTLYG QKPALAAVPG TSNHGWGLAV DLCGGVESYS
     TPQYAWMVAN AGRFGFIHPT WADQGNGREE PWHWEYAGS
//