ID   A0A1H0N101_9PSEU        Unreviewed;       546 AA.
AC   A0A1H0N101;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=SAMN05421507_104207 {ECO:0000313|EMBL:SDO86409.1};
OS   Lentzea jiangxiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=641025 {ECO:0000313|EMBL:SDO86409.1, ECO:0000313|Proteomes:UP000199691};
RN   [1] {ECO:0000313|EMBL:SDO86409.1, ECO:0000313|Proteomes:UP000199691}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.6609 {ECO:0000313|EMBL:SDO86409.1,
RC   ECO:0000313|Proteomes:UP000199691};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC       {ECO:0000256|ARBA:ARBA00006637}.
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DR   EMBL; FNIX01000004; SDO86409.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0N101; -.
DR   STRING; 641025.SAMN05421507_104207; -.
DR   OrthoDB; 3713880at2; -.
DR   Proteomes; UP000199691; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd18789; SF2_C_XPB; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR032438; ERCC3_RAD25_C.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032830; XPB/Ssl2_N.
DR   PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR   PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR   Pfam; PF16203; ERCC3_RAD25_C; 1.
DR   Pfam; PF13625; Helicase_C_3; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
FT   DOMAIN          190..344
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          398..544
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   546 AA;  60891 MW;  3902243E7590FE1A CRC64;
     MTDGPLIVQS DKTLLLEVDH PLADEARTSI APFAELERAP EHVHTYRVTP LALWNARAAG
     HDAEQVVDAL VRFSRYPVPQ PLLVDVVDTM SRFGRLVLAN NPAHGLVLHS NDRAVLEEVL
     RNKKIAPMFG ARIDDDTVVV HASERGRLKQ LLLKVGWPAE DEAGYVDGEA HPIELDEAGW
     KLRDYQRLAA QAFWAGGSGV VVLPCGAGKT LVGAAAMAEA QATTLILVTN TVAGRQWKRE
     LIARTSLTEE EIGEYSGERK EIRPVTIATY QVITRKSKGE YKHLELFDSR DWGLIVYDEV
     HLLPAPVFRM TADLQSRRRL GLTATLVRED GQEGDVFSLI GPKRYDVPWR DIEAQGWIAP
     AECTEVRVTL TDNERLLYAT AEPEERYKLC STARTKLPVV RRVLEQHPGE PALVIGAYLD
     QLDELGEELG APVIKGSTKN KEREELFDRF RRGELRTLVV SKVANFSIDL PEASVAVQVS
     GTFGSRQEEA QRLGRLLRPK GDGRQAHFYS VVSRDTLDTE YAAHRQRFLA EQGYAYKIVD
     ADDLVG
//