ID   A0A1H0NC26_9PSEU        Unreviewed;       210 AA.
AC   A0A1H0NC26;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Cation efflux family protein {ECO:0000313|EMBL:SDO89840.1};
GN   ORFNames=SAMN05192558_105282 {ECO:0000313|EMBL:SDO89840.1};
OS   Actinokineospora alba.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=504798 {ECO:0000313|EMBL:SDO89840.1, ECO:0000313|Proteomes:UP000199651};
RN   [1] {ECO:0000313|Proteomes:UP000199651}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBRC-M 10655 {ECO:0000313|Proteomes:UP000199651};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic
CC       vesicle membrane {ECO:0000256|ARBA:ARBA00004644}; Multi-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004644}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM163 family.
CC       {ECO:0000256|ARBA:ARBA00008731}.
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DR   EMBL; FNJB01000005; SDO89840.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0NC26; -.
DR   STRING; 504798.SAMN05421871_102332; -.
DR   OrthoDB; 9805136at2; -.
DR   Proteomes; UP000199651; Unassembled WGS sequence.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR   InterPro; IPR002524; Cation_efflux.
DR   InterPro; IPR027469; Cation_efflux_TMD_sf.
DR   InterPro; IPR026765; Tmem163.
DR   PANTHER; PTHR31937; TRANSMEMBRANE PROTEIN 163; 1.
DR   PANTHER; PTHR31937:SF2; TRANSMEMBRANE PROTEIN 163; 1.
DR   Pfam; PF01545; Cation_efflux; 1.
DR   SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199651};
KW   Synapse {ECO:0000256|ARBA:ARBA00023018};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        26..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   210 AA;  22027 MW;  5AD65207C200A179 CRC64;
     MSECACCAAP ATTVQRQQVL TRRVRLLVAA TISYNVVEAI IAITAGTIAS STALIGFGLD
     SVIEVASATA LAWQFSAKDH KTRERATLRI IAVSFFVLAA YVTVESIRAL LGAEAADHSP
     VGIALAAASL VIMPGLSYAQ RRAGRELGSA TAVADSKQTL LCTYLSAVLL VGLVLNSTLG
     WWWADPLAAL IIAAVAAKEG REAWRGNHCC
//