ID A0A1H0NPX2_9BURK Unreviewed; 1967 AA.
AC A0A1H0NPX2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN05216303_102759 {ECO:0000313|EMBL:SDO94681.1};
OS Rhodoferax sp. OV413.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Rhodoferax.
OX NCBI_TaxID=1855285 {ECO:0000313|EMBL:SDO94681.1, ECO:0000313|Proteomes:UP000199151};
RN [1] {ECO:0000313|Proteomes:UP000199151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV413 {ECO:0000313|Proteomes:UP000199151};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; FNJA01000002; SDO94681.1; -; Genomic_DNA.
DR STRING; 1855285.SAMN05216303_102759; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000199151; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 3.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199151};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 674..970
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1052..1528
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1637..1932
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 1967 AA; 213744 MW; 8CB223809BA88C15 CRC64;
MTQGTIRIRG ARQHNLKNLD LDIHTGELTV VTGPSGSGKS SLVFDTLFAE GQRRYVETFS
AYARQFLDRM DKPAVDKVEG VPPAIAIDQT NPVRSSRSTV GTMTELNDHL KLLFARAGNL
FDRVTALPVR HDTPESIYAE LCERAAAAQD PRLVLTFPVE LPGNTSAEEV TQWLSASGFT
RVQAEREVAV EAPATPAKPS KKAVAPATRK VLDVVADRFR IAGAEKARAL EAIEVAIKRG
GGRLNVYVLP AEEGAEPLLW KFSTGLHCAE SDVRYTDPIP SMFSFNSPVG ACETCKGFGR
VIGVDYGLVI PNDKLTLRSG AIKPMQTPAW QECQDDLMRH AEAAGIPRDT PYYKLTPEHQ
HWVINGSPNW NGKWNQHWFG VKRFFEYLET KSYKMHIRVL LSKYRSYTTC TACNGARLKT
ESLLWRLGSQ EDANAVLDPA KRHLPQGVDW SRAQLESLPG LCLHDLMLLP IDRLRRFFDL
QADRILGTRA EQGGDVQALK LLLDEITTRL KYLCDVGIGY LTLDRQSRTL SGGEVQRINL
TTALGTSLVN TLFVLDEPSI GLHPRDMHRI IEAMQRLRDA GNTLVVVEHD PAVMLAADRM
IDMGPGPGAR GGQIVFDGTT DDLRHADTLT GAYLGGRKTI GMGFKKLVTD STPRLVLEGA
REHNLQNVSV EFPLQRLVCI TGVSGSGKST LIQDVLAPAL MRHFGKATET PGLHDRLLGA
DYLSEVVFVD QSPIGKTARS NPASYVGAWD AIREIFANAA LSRQRGYTAS KFSFNSGDGR
CPTCGGSGFE HVEMQFLSDV YLRCPDCDGK RYRPEILEVT IERRAVADAR LQQLNVADVL
DLTVAEAAII FEGDRDVIRA LQPIVDVGLE YVKLGQPVPT LSGGEAQRLK LAGFLAEAAK
SSSASRQSVA KKGTLFLFDE PTTGLHFDDI AKLMRALRKL LDAGHSMVVI EHNLDVIRAS
DWLIDMGPEG GYGGGLVVVQ GMPEEVRLHA TSHTGAALRE YESTLGIGAQ VVKEKTPAWL
AQQAARVVPP NAIQIVNAKE HNLKSLSVDI PRGQFNVVTG VSGSGKSTLA FDILFNEGQR
RYLESLNAYA RSIVQPAGRP EVDAVYGIPP TVAIEQRLSR GGRKSTVGTT TEVWHFLRLL
YVKLGTQHCV FDGAAVQPQT PDSIAAQLLK TFRGQHIGLL APLVINRKGV YTELADWARP
RNYTHLRVDG DFLPTTGFPR IDRFKEHTVE LPVLSLDVGP GNEARLREGL ATALEHGKGV
VHVLVGIDGL KEAMADGLPT AHIGKVMVFS SKRACPVCST SYAELDPRLF SYNSKHGWCP
DCVGTGVKLT KDQRAVFDDS VRADDTGGRE QTFAEPEVED LHDVACPTCQ GTRLNANARA
VRFANVGITD LARLSVTDIR VWVQALQVAG QMSQREVDIA RDLVPEIQSR LEFLEEVGLG
YLTLDRGAPT LSGGEAQRIR LAAQLGSNLQ GVCYILDEPT IGLHARDNHI LLNALHKLSS
KGNTLVVVEH DEDTIRRADH IIDIGPSAGK RGGRLVAQGA VADISDATES VTGRYLLHAM
RHPLQARRAV GTFDPAAVAV PVADLPYVAP TAKSKAAAKK KAADAPEAVA VAEPLQWLTV
SGATMHNLQN VSVQIPLKRL VAVTGVSGSG KSTLARDVLL ANVQTAVVQR STKAGRDSWA
AGQRPAWLGC ADVAGFAAID RVLEVDQTPI GKTPRSCPAT YIGFWDTIRK LFADTLEARA
RGYGPARFSF NTGEGRCPSC EGQGLRTIAM SFMPDVKVKC ETCHGARFNP ETLTVTWRGK
SIGDVLQMEV DEAVDFFAVM PVIAYPLQLL KDVGLGYLTI GQPSPTLSGG EAQRIKLVTE
LSKVRDDITR RGQKAPHTLY VLDEPTVGLH MADVEKLIRV LHRLVDGGHS VVVIEHDLDV
IAESDWIIDL GPDGGNAGGR IVAAAPPEAV VALGTATGVA LKPVLAR
//
