ID A0A1H0RDW8_9BURK Unreviewed; 397 AA.
AC A0A1H0RDW8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Acetyl-CoA C-acetyltransferase {ECO:0000313|EMBL:SDP27108.1};
GN ORFNames=SAMN05216303_103540 {ECO:0000313|EMBL:SDP27108.1};
OS Rhodoferax sp. OV413.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Rhodoferax.
OX NCBI_TaxID=1855285 {ECO:0000313|EMBL:SDP27108.1, ECO:0000313|Proteomes:UP000199151};
RN [1] {ECO:0000313|Proteomes:UP000199151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV413 {ECO:0000313|Proteomes:UP000199151};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; FNJA01000003; SDP27108.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0RDW8; -.
DR STRING; 1855285.SAMN05216303_103540; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000199151; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF144; ACYL-COA THIOLASE-RELATED; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000199151};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SDP27108.1}.
FT DOMAIN 9..264
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 275..395
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 93
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 353
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 383
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 397 AA; 40387 MW; 1306AB5E1B241EDB CRC64;
MSIPAADPIV ILGAARTPMG GFQGDFAALA AHDLGGAAIR AAVARAGVDP ARIGEALLGN
CLMAGQGQAP ARQAAFKGGL PQSCGAVTLS KMCGSGMKAA MLAHDMLRAG SFDVMLAGGM
ESMTNAPHLL PKGRSGIRIG HGQVLDHMML DGLEDAYQPG RSMGTFGEDC AAKYGFTRAA
QDSFATTSVQ RAQAAITSGA FAAEITPVTV PGRNGDTLVS IDEGPGKIRL DKIPTLRPAF
KKDGSITAAS SSSINDGAAA LVLALASTAQ RLGAQPLARV VGHATHAQAP EWFATAPLGA
VQKLLAQTGW SVADVDLWEV NEAFAVVPMA LMAELDIAHS IVNVHGGACA LGHPIGASGA
RILVTLLYAL RARGLRRGVA TLCIGGGEAT AMALELL
//
