ID A0A1H0SFI2_9PSEU Unreviewed; 338 AA.
AC A0A1H0SFI2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase-3 {ECO:0000313|EMBL:SDP40460.1};
GN ORFNames=SAMN05421507_10843 {ECO:0000313|EMBL:SDP40460.1};
OS Lentzea jiangxiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=641025 {ECO:0000313|EMBL:SDP40460.1, ECO:0000313|Proteomes:UP000199691};
RN [1] {ECO:0000313|EMBL:SDP40460.1, ECO:0000313|Proteomes:UP000199691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.6609 {ECO:0000313|EMBL:SDP40460.1,
RC ECO:0000313|Proteomes:UP000199691};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Antibiotic biosynthesis. {ECO:0000256|ARBA:ARBA00004792}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
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DR EMBL; FNIX01000008; SDP40460.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0SFI2; -.
DR STRING; 641025.SAMN05421507_10843; -.
DR OrthoDB; 6637632at2; -.
DR Proteomes; UP000199691; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR34069; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3; 1.
DR PANTHER; PTHR34069:SF2; BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194}.
FT DOMAIN 110..186
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08545"
FT DOMAIN 248..337
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 338 AA; 36220 MW; 26463A3DDB21D7C0 CRC64;
MTVHFGVVSL GHVLGDPVEV ASAAAGYTAD VDRVLGWGYR TFHRAGDGVG LTDLAAEAGA
KALGDAGVQP HEVDLVVLAM SDLSEHLYWD AAGATQAKIG AHRSENVLLT QACGGGVAAF
DIVAGKFATH PGYSTALIIG ANRVCEPYWN RMEINTSIFS DGAAAAVVKR DHPRNRWLTT
EIISDGRYAD FMMMDVGAAA RPFAGQRDIG VKSPQKRLEE FFAGDIRKMF EFVSTIRTNN
HEVVRRACER AGTTPADLRK LLHLHDSVPA MTLLAKDLDH GPEWTNTEVA QALGHVGCAD
QLMSLEHYLA AGELTEGDVV ALTSTASGMH WLCTLLAI
//
