ID   A0A1H0TCK1_9MICO        Unreviewed;       504 AA.
AC   A0A1H0TCK1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Mannitol 2-dehydrogenase {ECO:0000313|EMBL:SDP51747.1};
GN   ORFNames=SAMN04489867_2737 {ECO:0000313|EMBL:SDP51747.1};
OS   Pedococcus dokdonensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC   Pedococcus.
OX   NCBI_TaxID=443156 {ECO:0000313|EMBL:SDP51747.1, ECO:0000313|Proteomes:UP000199077};
RN   [1] {ECO:0000313|Proteomes:UP000199077}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22329 {ECO:0000313|Proteomes:UP000199077};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT629711; SDP51747.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0TCK1; -.
DR   STRING; 443156.SAMN04489867_2737; -.
DR   OrthoDB; 271711at2; -.
DR   Proteomes; UP000199077; Chromosome i.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR000669; Mannitol_DH.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR023027; Mannitol_DH_CS.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR   PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE   4: Predicted;
FT   DOMAIN          34..202
FT                   /note="Mannitol dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01232"
FT   DOMAIN          231..471
FT                   /note="Mannitol dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08125"
SQ   SEQUENCE   504 AA;  55354 MW;  3564F95704264648 CRC64;
     MTGVAPVALS DDTLGNLRAE VGRPAYDRSE VTASIVHFGV GGFHRAHEAM YLDALMNDGQ
     ALEWGLCGVG ALPHDRRIID TLRQQDGLYT LVVKHPDGHR EPRVIGSIVE VMFAPDDPQA
     VVDRLADDQT RIVSLTITEG GYLVNQVTGE FDADDPSIQA DLAADFAGGD GPTTVFGFIV
     AGLDRRRREG RAPFTVMSCD NLPDNGDVAK KMIGAFARAR DPELADWMAA EVAFPNCMVD
     RITPVTAPED IAHLADDFGV ADAWPVVCEP FTQWVLEDRF GQGRPPFEDA GVQMVDDVVP
     YELMKLRLLN ASHQALCYLG YLSGYRYAHE VCQDPLFARF LLSYMEDEGS PTLPEVPGVD
     LDAYRHQLVE RFANPEVRDT LARLCAESSD RIPKWLVPVI KANLRDGGAV ELSALVVASW
     ARYAEGVDEQ GRPIEVVDRL RDRVMAAAAR QSDDPLAFIR DRDLFDDLAD DERFATAYTA
     ALDSLHRNGA RATLESRAAL GART
//