ID A0A1H0VI05_9ACTN Unreviewed; 506 AA.
AC A0A1H0VI05;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Nucleobase:cation symporter-1, NCS1 family {ECO:0000313|EMBL:SDP78080.1};
GN ORFNames=SAMN04487981_14015 {ECO:0000313|EMBL:SDP78080.1};
OS Streptomyces sp. cf386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1761904 {ECO:0000313|EMBL:SDP78080.1, ECO:0000313|Proteomes:UP000198720};
RN [1] {ECO:0000313|Proteomes:UP000198720}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF386 {ECO:0000313|Proteomes:UP000198720};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNHV01000040; SDP78080.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0VI05; -.
DR STRING; 1761904.SAMN04487981_14015; -.
DR OrthoDB; 6083029at2; -.
DR Proteomes; UP000198720; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR PANTHER; PTHR30618:SF6; PERMEASE-RELATED; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198720};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 506 AA; 53367 MW; 4DC433EAC7A798D9 CRC64;
MTATDSADAD RTATPPGYSP RLYNADLAPA TERKWGAFSI FNVWTSDVHS LYGYFLAASL
FLVAGNTFKF LIGIGVGSLI IYWLMTLIGK AGVKTGVPYP VLARASFGTF GANVPALVRA
VVATFWYGAQ TSAAAGAIVA FLVRYDGPKH LHETSRLFDH SGLEVLCYLG VWAAQLLIIS
KGMETVRRFQ DFAGPAVWLM MLILAIALSV KAGALSFSVD MPSGDLAALA KSATGLDVSP
GSLAAIAAIA ATWVTYFAAL FLNFGDFARF TPDTKALKKG NIWGLPVNLI LFSLVAAVTT
AAASTVYGEV LLEPAEISAK FDSAFLVLLA ALTFAVATLG INVVANFVSP AFDFANVAPK
YVTFRRGGLI AAVIALLLYP LHPWDNAPSF VNAIGSTMGP IFGVIVVDYY LIRKTQLNVP
ALYDEGGEFR FQGGWNVRAF AAGVVGAIFS SILPVYGPSG YGATLGPYSW FIGVVVAGVL
YFAFSGGKSP LTARTAAVAA PEATEA
//
