ID   A0A1H0W6Z2_9PSEU        Unreviewed;       763 AA.
AC   A0A1H0W6Z2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SDP86507.1};
GN   ORFNames=SAMN05192558_11845 {ECO:0000313|EMBL:SDP86507.1};
OS   Actinokineospora alba.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=504798 {ECO:0000313|EMBL:SDP86507.1, ECO:0000313|Proteomes:UP000199651};
RN   [1] {ECO:0000313|Proteomes:UP000199651}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBRC-M 10655 {ECO:0000313|Proteomes:UP000199651};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNJB01000018; SDP86507.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0W6Z2; -.
DR   STRING; 504798.SAMN05421871_11745; -.
DR   OrthoDB; 5241784at2; -.
DR   Proteomes; UP000199651; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 2.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF63; SENSOR HISTIDINE KINASE DESK; 1.
DR   Pfam; PF07730; HisKA_3; 2.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SDP86507.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199651};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        21..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        408..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        437..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        470..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        497..522
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        534..556
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          197..261
FT                   /note="Signal transduction histidine kinase subgroup 3
FT                   dimerisation and phosphoacceptor"
FT                   /evidence="ECO:0000259|Pfam:PF07730"
FT   DOMAIN          576..640
FT                   /note="Signal transduction histidine kinase subgroup 3
FT                   dimerisation and phosphoacceptor"
FT                   /evidence="ECO:0000259|Pfam:PF07730"
SQ   SEQUENCE   763 AA;  81018 MW;  37FB64B0B75824B3 CRC64;
     MRWFRLSSTP WRPHGTPFAS GPLLAPLLAR AIVAAVYSGL CVVAFLHVLE SAPAFSVALF
     AAVALLILLA LQVCYISRPG GPPRSPLTYW VLAAQTCLVF VPAQQFGQAW VALPSLLAGT
     VLLVLPPAAA VTAFVAILVV TARTQEMLTH SVLDVAYIVA GGLVAALEVF GLTRLAGLIT
     DLHAARSELG KVAVARERTR FARDLHDLLG LSLAAIGPKS AAASAALTTD PDKARAELRE
     ILVVARHALA DVRLISSGYR ELSLREESRT VEALLAASNV DVRMELNHGE LPAHIRSVVV
     AVLRAGVANV LHHTSVARCD ITMRQAGRTL ALDIVDDGVT GRCATEDSSF DGGLDSLADR
     VRALGGSLTE GPDPDGRFGL HLAIPVGSRV EHAAASDEIE EGPRYATLLA TGLMNVVFVG
     FGCAAMLHLL YLTRDPVVLW FGAGCLLALV ALQLLWVSRP GVRIGSPSRY VVVAVQAMLV
     YLPLAVFPHA WASVPGLLAG TALLVFRPAM GWLGFGAVVA SVPWAQGSSE LIDVILAVTA
     TVITGLVTYG LTWMAGSVSE LRAARRALAR AAVTRERQRF ARDLHDLLGL SLSAITLKAE
     LAHRAMKVDP VRVVAELGEI VSIARLALAD VRLVAGGYRD LSLNEESRSV ESVLAAANVD
     VRMDLRYGEL RPEVRTVLAT VLREGVTNVL RHSRGAHCEI SVRRHADMVV LEIVNDGVSV
     PFAREGVGNG IRNLTERVAV VGGHLVAGVG DDGMFRLRAE VPA
//