ID A0A1H0XQ39_9ACTN Unreviewed; 763 AA.
AC A0A1H0XQ39;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=aminodeoxychorismate synthase {ECO:0000256|ARBA:ARBA00013139};
DE EC=2.6.1.85 {ECO:0000256|ARBA:ARBA00013139};
GN ORFNames=SAMN05428996_0197 {ECO:0000313|EMBL:SDQ05057.1};
OS Quadrisphaera sp. DSM 44207.
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Quadrisphaera.
OX NCBI_TaxID=1881057 {ECO:0000313|EMBL:SDQ05057.1, ECO:0000313|Proteomes:UP000199015};
RN [1] {ECO:0000313|EMBL:SDQ05057.1, ECO:0000313|Proteomes:UP000199015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44207 {ECO:0000313|EMBL:SDQ05057.1,
RC ECO:0000313|Proteomes:UP000199015};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the anthranilate
CC synthase component I family. {ECO:0000256|ARBA:ARBA00005970}.
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DR EMBL; FNKA01000001; SDQ05057.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0XQ39; -.
DR STRING; 1881057.SAMN05428996_0197; -.
DR Proteomes; UP000199015; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd01743; GATase1_Anthranilate_Synthase; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR006221; TrpG/PapA_dom.
DR NCBIfam; TIGR00566; trpG_papA; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF18; AMINODEOXYCHORISMATE SYNTHASE; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR Pfam; PF00117; GATase; 1.
DR PRINTS; PR00097; ANTSNTHASEII.
DR PRINTS; PR00099; CPSGATASE.
DR PRINTS; PR00096; GATASE.
DR SUPFAM; SSF56322; ADC synthase; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 3: Inferred from homology;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605};
KW Reference proteome {ECO:0000313|Proteomes:UP000199015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 17..204
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT DOMAIN 266..402
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 467..732
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT REGION 210..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 101
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 189
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 191
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 763 AA; 78625 MW; 24A9EB7B48874A79 CRC64;
MAASRPRRAS GAGARVLLVD NQDSYTWTLR HLLAAATGGL PRVVDHREAA AGALPLLAAG
DADLVVISAG PGHPARDRDF AGSRAVLEGA RELGVPVLGV CLGHQGLAAM AGADVVPAPQ
PRHGHLTRVH HGGRDVFAGV PDGFTAVRYH SLCVAEPLPE ELEALARAED GVVMALRVRD
RPAWGLQFHP ESVATEHGAA LLAGVLREAG LPGPGGGRRS GPRGGPGDGS RVPRGSARPG
AGEPPSAPVR LRVAHRALGR AVDAEAAFAR LFAASGTAFW LDSARTDPGR GAVSVLGDAE
GELAEVVLLD AASGTTRVRC GGGAVLERRV PVLEHLRERL RARRVEGPAL PLGVAGGWVG
WHGYEAGSST MRPTRHRAAT PDAAWVLPQR LVLVDHAGDE THLVHLEPAD AAGDARSAAA
LDALAEALHD LQPLPPPADG ADGADGADGA DGADGAGAVR PVWTRDRAGY TADVEAVQEL
LRQGEVYEAC LTTGVRVPAS GAPGDGFARY RRLRRANPAP YAAYLRLRDV DGTDGTDVEV
LCSSPERFLR VDGDGWAESE PIKGTAPRLA DPAQDAAAAR ALAADPKARA ENLMVVDLVR
NDLARVCEPG TVAVPALMAV RSYATVHQLV TTVRGRLAAG EDALSCLDSC FPPGSMTGAP
KVRAVEVLEQ LEQEARGVYS GALGWIGPGG EADLAVVIRT AVRAGGTWRV GTGGAVVLGS
DPAAEHDEVL LKAAPLLAVL SPAAAAAGRP PGRRGSAARA PGR
//
