ID A0A1H0XQD6_9ACTN Unreviewed; 732 AA.
AC A0A1H0XQD6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN ORFNames=SAMN05428996_0204 {ECO:0000313|EMBL:SDQ05142.1};
OS Quadrisphaera sp. DSM 44207.
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Quadrisphaera.
OX NCBI_TaxID=1881057 {ECO:0000313|EMBL:SDQ05142.1, ECO:0000313|Proteomes:UP000199015};
RN [1] {ECO:0000313|EMBL:SDQ05142.1, ECO:0000313|Proteomes:UP000199015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44207 {ECO:0000313|EMBL:SDQ05142.1,
RC ECO:0000313|Proteomes:UP000199015};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
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DR EMBL; FNKA01000001; SDQ05142.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H0XQD6; -.
DR STRING; 1881057.SAMN05428996_0204; -.
DR Proteomes; UP000199015; Unassembled WGS sequence.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR038417; Alpga-gal_N_sf.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR031705; Glyco_hydro_36_C.
DR InterPro; IPR031704; Glyco_hydro_36_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF16874; Glyco_hydro_36C; 1.
DR Pfam; PF16875; Glyco_hydro_36N; 1.
DR Pfam; PF02065; Melibiase; 1.
DR PRINTS; PR00743; GLHYDRLASE36.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000199015}.
FT DOMAIN 41..279
FT /note="Glycosyl hydrolase family 36 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16875"
FT DOMAIN 638..718
FT /note="Glycosyl hydrolase family 36 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16874"
SQ SEQUENCE 732 AA; 78805 MW; 0D283576FADC6F28 CRC64;
MTALQPLTGP ERVPDADPSE RLVHLSAAGV SLVLDCRGPA LPAVLHWGAA LGPLDGEGLR
ALAAAALPPS VPSAPDVPAL VSLVPAAASG WMGLPGLRGS RADGSDWSPD LAVEEVEVGR
EDGRGGLVVV RAADPAAGLA LELRVELTPS GLVRARAAVR NTAPQAPYRL DGLVLALPVP
AEAAQLLDLT GRWGRERSPQ RTAFTIGSRV RDNRRGRTGA DATLVLAACE PGAGFRAGEV
WGVHVGWSGN HRTYAERLPS GEAVLGGGEL LLPGEVRLQP GEAYETPWLY GSCGHGLDEV
SARFHDWMRA RPGHPRSPRP VIANTWEAVY FDHDLGRLTA LADAAAQVGA ERFVLDDGWF
RHRRDDRAGL GDWYVDEDVW PQGLHPLVQH VRGLGMQFGL WIEPEMVNPD SDLARAHPEW
VMAPGERQPL LVRHQQVLDL GHPGAYEHVL ERISALVAEH RIDYLKWDHN RDLTEAGHWP
TGAPGVHAQT LAVYRLVDEL RARHPHLEIE SCSSGGARVD LGILQRTDRV WASDCIDALE
RQGIQRWTGL LLPPELVGSH VGAGRSHTTS RVHDLSFRAG TALFGHFGIE WDLLAATEEE
RAELARWVAL YKELRGLLHS GRVVRGDHPD PALLVHGVVA ADAARAVFAL VATATSEVSP
PGRVRLPGLD PQRRYRVRPL PPGDSPPGVH GAPVRWLDGD GVVLPGAALS LAGLQAPALH
PDHLFLLDAT AE
//
