ID   A0A1H0YID4_9BACI        Unreviewed;       609 AA.
AC   A0A1H0YID4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SDQ14790.1};
GN   ORFNames=SAMN05216231_0663 {ECO:0000313|EMBL:SDQ14790.1};
OS   Virgibacillus salinus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX   NCBI_TaxID=553311 {ECO:0000313|EMBL:SDQ14790.1, ECO:0000313|Proteomes:UP000199444};
RN   [1] {ECO:0000313|EMBL:SDQ14790.1, ECO:0000313|Proteomes:UP000199444}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.10449 {ECO:0000313|EMBL:SDQ14790.1,
RC   ECO:0000313|Proteomes:UP000199444};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FNKD01000001; SDQ14790.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0YID4; -.
DR   STRING; 553311.SAMN05216231_0663; -.
DR   Proteomes; UP000199444; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199444};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          281..564
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   609 AA;  67996 MW;  8D281B8AF8417B97 CRC64;
     MTYRIRMSLL ILLDSLIVSL AIFVASWIVY PDISVFAMPA LLISSIALLF FHHLWAFIYK
     LYNKVWAYAS VGELIAIVQA ITLSIVSAGV VQYIVNDFAI YRRALVVTWM LHVILIGGSR
     FLWRIVRDRY ITEGTNKKRT LIVGAGSAGA MIVRQLKNNN NTSELQPVAF VDDDFSKQKM
     QLYNLPVMGR VKDISKIVEK KSIEHIVIAI PSLRNGALNK VIVECNKTNA KTQMIPKIED
     IMTGKVSVSQ LKNVEVEDLL GREPVELDID AISENVTNAT ILVTGAGGSI GSEICRQLMR
     FTPSKIVLVG HGEFSIYTIE MELREKFGNM GIEIVPIIGD VQDRNRIFEI VEEHKPTTIY
     HAAAHKHVPL MEYNPYEAVK NNVLGTKNVA ESADAFCVET FVLISSDKAV NPTNVMGATK
     RIAEMVIQDL SFQSKTKFVA VRFGNVLGSS GSVIPLFKKQ IEKGGPVTVT HPEMTRYFMT
     IPEASRLVIQ AGTLARGGEI FVLDMGEPVK IVDLAKNLIK LSGFTEEEIT INYTGKRPGE
     KMFEELLSTD EVYPKQVFDK IYIGKTNRVN TDVVQSITSE FQYLSINGLK EELLLIANQQ
     NNIKEIVIN
//