ID   A0A1H0YRS2_9EURY        Unreviewed;       634 AA.
AC   A0A1H0YRS2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Gamma-glutamyltransferase {ECO:0000313|EMBL:RDI72637.1, ECO:0000313|EMBL:SDQ17768.1};
DE            EC=2.3.2.2 {ECO:0000313|EMBL:RDI72637.1};
GN   Name=ggt {ECO:0000313|EMBL:RDI72637.1};
GN   ORFNames=DWB78_13410 {ECO:0000313|EMBL:RDI72637.1}, SAMN05216278_0799
GN   {ECO:0000313|EMBL:SDQ17768.1};
OS   Halopelagius longus.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae.
OX   NCBI_TaxID=1236180 {ECO:0000313|EMBL:SDQ17768.1, ECO:0000313|Proteomes:UP000199289};
RN   [1] {ECO:0000313|EMBL:SDQ17768.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.12397 {ECO:0000313|EMBL:SDQ17768.1};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000199289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.12397 {ECO:0000313|Proteomes:UP000199289};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:RDI72637.1, ECO:0000313|Proteomes:UP000255421}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BC12-B1 {ECO:0000313|EMBL:RDI72637.1,
RC   ECO:0000313|Proteomes:UP000255421};
RA   Zhang X.;
RT   "Genome sequence of extremly halophilic archaeon Halopelagius longus strain
RT   BC12-B1.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QQST01000001; RDI72637.1; -; Genomic_DNA.
DR   EMBL; FNKQ01000001; SDQ17768.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0YRS2; -.
DR   OrthoDB; 183046at2157; -.
DR   Proteomes; UP000199289; Unassembled WGS sequence.
DR   Proteomes; UP000255421; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IEA:InterPro.
DR   GO; GO:0103068; F:leukotriene C4 gamma-glutamyl transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR   Gene3D; 1.10.246.130; -; 1.
DR   Gene3D; 3.60.20.40; -; 1.
DR   InterPro; IPR043138; GGT_lsub_C.
DR   InterPro; IPR000101; GGT_peptidase.
DR   InterPro; IPR043137; GGT_ssub.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   NCBIfam; TIGR00066; g_glut_trans; 1.
DR   PANTHER; PTHR43199; GLUTATHIONE HYDROLASE; 1.
DR   PANTHER; PTHR43199:SF1; GLUTATHIONE HYDROLASE PROENZYME; 1.
DR   Pfam; PF01019; G_glu_transpept; 1.
DR   PRINTS; PR01210; GGTRANSPTASE.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000313|EMBL:RDI72637.1}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDQ17768.1}.
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          403..462
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          496..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        429..462
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        513..527
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   634 AA;  67392 MW;  3133D9B96E687AD3 CRC64;
     MDRSDESPAD ESNDAETDET AARFTATKRA FLRGSGVALG AGVLPAGAGT AVGTTGGKSN
     SVAKGGGGMV SSVHRQATNA GVEVLKDGGN AVDAAVAVQF ALNVVQPHSS GIGGGGFMLV
     YSAEEDEIIA IDNRERAPLG AQPDMFLNEQ GEEVPFLERH TNGKAVGVPG TLKAADVAVK
     RFGTKELGEL IEPAVELAAP DGETVTVDEF LADSIAANVE EGSFTSTAKE VFAPGGDPLQ
     EGDELAQPDL ADTLRTIRDE GIGPFYKGEI AEDIAETVQG AARYRKTGGN MTVDDLGRYN
     VEITRPVHVT YEGDAHDITV RTMRSPTSGG YVIGQILSLL EPFDLAQYDR RSFDVYHRMI
     EAFQLAFADR NEYLGDEEFV DIPWQGFLDE EYLDERRKII DPKKATAATR EPGDPFAYQP
     GGQYYTSPRD VEEAQNVSNA SGNKGKKTGT EEPSGQTTHF TTADADGNLV SWTSTIEQLF
     GSGIMVPGRG FMLNNELTDF DSEPGGPNEV QPEKRPLSST SPTIVTRDGD PFLTVGSPGG
     WSIIHTVSQI LLNVAEFGMD IDEAVAEPRV YSATGTWVQA EGGVPDGVVD ELNAAGHDVS
     VVETIGNAQS IRIEDDGEYV GVADKRRNGC AKSP
//