ID   A0A1H0ZWY1_9FLAO        Unreviewed;      1046 AA.
AC   A0A1H0ZWY1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=SAMN05421664_1108 {ECO:0000313|EMBL:SDQ31576.1};
OS   Chryseobacterium soldanellicola.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC   Chryseobacterium group; Chryseobacterium.
OX   NCBI_TaxID=311333 {ECO:0000313|EMBL:SDQ31576.1, ECO:0000313|Proteomes:UP000199627};
RN   [1] {ECO:0000313|EMBL:SDQ31576.1, ECO:0000313|Proteomes:UP000199627}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17072 {ECO:0000313|EMBL:SDQ31576.1,
RC   ECO:0000313|Proteomes:UP000199627};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; FNKL01000002; SDQ31576.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H0ZWY1; -.
DR   STRING; 311333.SAMN05421664_1108; -.
DR   OrthoDB; 9810135at2; -.
DR   Proteomes; UP000199627; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:SDQ31576.1};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          1..474
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          475..750
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   BINDING         10..17
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   1046 AA;  122752 MW;  98131FA2F89B06E1 CRC64;
     MQNSYTVINA SAGSGKTYAL VQRLLMICLR YPNQQHSIRN ILALTFTNKA ANEMKERILT
     WLGNFSADNF AENPDLKNIQ QAFEQEGLKI TIDELHYRSK KLLDYVLHNY STLNIGTIDR
     FNSRLVRSFS YELGLAKNFN LKIEAEPFLI EAVDKMLDQI GENDAISSSF MDYVDYSLEN
     NERINLNKNL YDSAKEFVKD IHYEHLKSNK SFDDTNYENI KNTIRKEISF NKKQAIEVAT
     NSIQLFQSRN IEIEDFSGGK KNGLGLFFNE IIRFYNKERA TFPFPTNEET ALANYQKGAA
     TKSKSKETDI LEILDQLLEN RMQLIILFIE TQKKEKILSA LLPLKVNKDI QDELRKIEEE
     NDLVLLSKFN ILINENLRNE PSAFIYEKVG SQFQHYFFDE FQDTSELQWQ NFVPLRDHSV
     STDNTSFTLV GDPKQSIYRF RGGESKLMLD IINKKEISPK EAELLVLKDN WRSAKNIVQF
     NNELYQYHSI NLEEEHKNIF GTDGEQSSKS SISGRVKVNL IENLTNEDFY NDTSERMRKD
     IQESLDNGFK FSDITILCRG NFDIFSYSQK LGNLKVNYKG EETNIKTISD KGLTLELSHT
     LKAVIEFLKW ETNPKNKPNL IMMMYHLNKL GRIHMLDFTL EMKEILEIGS HEEILQFIQE
     KYSLKLKQDN FPKFNLYNFV EYYINEFSVE NKETDFLLNF LEMLFNFTQN AGASTKEFLK
     YWDEEASTYT IQASENIDAI QIMTIHKAKG LEFPIVFIPM MNKNRDAEFT NWFETNNDDA
     LKSVNINQFN KNLEVYDEEI QKFNKINSYK NLVDRLCLQY VATTRPVEQL FFYIQKANKT
     SNNLELLEFL QTKNINESDE FDLYEVHPEM LKKYSKDKTS SFKTQDIRNL KNINEKSTSI
     KIATPSKNYQ VRNEKVRIGL FVHELLSKIN TKKDVEKVLE SYVLEGQITR DEKNEIQETL
     QQIIHNYTEF FDEKWTVINE KDIMISENGE SRIYRPDRIL KNDEGYIIVD FKTGEETEKN
     DRQIENYRKI LEGLGRKILK TQLIYL
//