ID A0A1H1ASX3_9ACTN Unreviewed; 622 AA.
AC A0A1H1ASX3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ATP-dependent RNA helicase DeaD {ECO:0000313|EMBL:SDQ42785.1};
GN ORFNames=SAMN05428996_1664 {ECO:0000313|EMBL:SDQ42785.1};
OS Quadrisphaera sp. DSM 44207.
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Quadrisphaera.
OX NCBI_TaxID=1881057 {ECO:0000313|EMBL:SDQ42785.1, ECO:0000313|Proteomes:UP000199015};
RN [1] {ECO:0000313|EMBL:SDQ42785.1, ECO:0000313|Proteomes:UP000199015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44207 {ECO:0000313|EMBL:SDQ42785.1,
RC ECO:0000313|Proteomes:UP000199015};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
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DR EMBL; FNKA01000002; SDQ42785.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1ASX3; -.
DR STRING; 1881057.SAMN05428996_1664; -.
DR OrthoDB; 9805696at2; -.
DR Proteomes; UP000199015; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd12252; RRM_DbpA; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR005580; DbpA/CsdA_RNA-bd_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959:SF19; ATP-DEPENDENT RNA HELICASE DBPA; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF03880; DbpA; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492};
KW Reference proteome {ECO:0000313|Proteomes:UP000199015}.
FT DOMAIN 29..57
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 60..236
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 266..411
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 502..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 29..57
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
SQ SEQUENCE 622 AA; 65174 MW; 177220E9D20F7816 CRC64;
MSAPAVPDPS TPASAAGAAA GAATGAAAGR FADLGLRPEL LEALAGLGYE EPTPIQTEAV
PVLLTGRDVV GQAATGTGKT AAFALPLLQR ITEGGPQRAE EGAPSALVLV PTRELAIQVA
EAVQRYGQRL RVRVLAVYGG QAITSQLRAL RAGVDVVVAT PGRALDHLRR GSLRLDAVRV
VVLDEADEML DMGFAEDIEA ILQATPEQRQ TLLFSATMPP RIDGIARQHL RDPVQLRVAR
EAPAAGEAPL VRQSAYVVAR PHRAAALGRV LDVEAPAAAI VFCRSRGEVD ELAEVLGARG
HRAEALHGGM SQEQRDRVMG RLRSRTADLL VATDVAARGL DVEHLTHVVN YGVPAAPESY
VHRIGRVGRG GREGVAITLA EPRERRALAA IERATGQRIP VHRVPSVEDL RAARLRRTRA
ALVEAVRTDG ASAGARAGLG PYRELAASVA EAEGRDGSLH GSLDAVEREA LLDVAAAALA
LAAAGGGSPE DDVEIPEATQ RGAAPALGAR PPRAGTPHRA ASERAGGARP RVAGRGRGRS
DSTTRLFIGL GRAAGIRPQD LVGAIANESP VSGREIGAVE IADRFSLVEV PESTADEVVR
ALRGSIIRGR RATVRRERYE AR
//
